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Shark liver oil and cancer

What is shark liver oil

Shark liver oil is a dietary supplement extracted from the livers of sharks, especially from species such as dogfish and Greenland sharks. It is rich in omega-3 fatty acids, vitamins A and D, as well as alkylglycerols and squalene. Shark liver oil is often used for its potential health benefits, including supporting the immune system, alleviating inflammation, and improving skin health. It is also used in alternative treatments, but more research is needed to confirm its effectiveness and safety.

Shark liver oil has been known for many years for its potential health benefits, especially due to its high content of omega-3 fatty acids.

These nutrients play an important role in our health, including:

Vitamin A

Necessary for the immune system and cell growth. Furthermore, it is important for vision.

Vitamin D

Vitamin D supports the immune system and contributes to strong bones and teeth.

Omega-3 fatty acids

Omega-3 fatty acids are essential for our health and can contribute to reducing the risk of cardiovascular disease, inflammation, and certain types of cancer. Shark liver oil is a rich source of these fatty acids.

Alkoxyglycerol

Shark liver oil contains a substance called alkoxyglycerol (alkylglycerols), which in experiments has shown promising results by influencing the growth and spread of certain cancer cells [2].

The immune system

Some researchers believe that shark liver oil can strengthen the immune system, which may help the body fight cancer cells more effectively [4].

Antioxidants

Shark liver oil also contains antioxidants, which can protect cells from damage caused by free radicals that may contribute to the development of cancer.

Targeted inhibition of growth and metastasis

Recent research indicates that the specific alkylglycerols found in shark liver oil may exert a selective effect, specifically targeting cancer cells while leaving the body’s healthy cells largely unaffected [2].

Furthermore, evidence suggests that the oil’s components act as an effective barrier against metastasis by making it more difficult for cancer cells to invade neighboring tissue and spread to other organs [5].

By inhibiting the formation of new blood vessels (anti-angiogenesis), shark liver oil may also contribute to “starving” the tumor of oxygen and nutrients, further limiting its capacity to grow [3].

Advantages of shark liver oil

Heart health

The omega-3 fatty acids in shark liver oil can contribute to lowering triglyceride levels, reducing blood pressure, and decreasing the risk of blood clots.

Brain function

Omega-3 fatty acids are crucial for brain development and function.

Joint health

Studies suggest that omega-3 fatty acids can alleviate symptoms of rheumatoid arthritis.

Immune defense

Vitamins A and D in shark liver oil strengthen the immune system.

Risks

High vitamin A content

An excessively high intake of vitamin A can be harmful, especially for pregnant and breastfeeding women.

High price

Shark liver oil is often more expensive than other sources of omega-3 fatty acids, such as fish oil, though the latter does not contain all the same compounds.

Contamination

Sharks are predators and can bioaccumulate environmental toxins in their bodies. Therefore, it is important to choose shark liver oil from certified sources.

Alternatives

There are other sources of omega-3 fatty acids, such as fish oil and krill oil, which may be less contaminated.

Vegetarian alternatives

For vegans and vegetarians, there are plant-based omega-3 sources such as flaxseed oil and algae oil. Since these are assumed to contain limited amounts of environmental toxins (depending on where they are harvested), they are, of course, a possible alternative for everyone.

Research

Not many trials have been conducted with shark liver oil in humans. The experiments that have been done are primarily on mice and rats. However, these have shown absolutely interesting results.

You can get an overview of research here:

PubMed – search for “shark liver oil and cancer”.

Conclusion

Shark liver oil can be a good supplement to a healthy diet, but it is important to consider the benefits and risks.

Although there are promising results from laboratory experiments, there is still limited research in humans, and more large-scale clinical trials are needed to confirm the potential benefits.

Shark liver oil should never be considered a substitute for relevant cancer treatment. Talk to your practitioner about whether it would be beneficial in your situation.

Back to Dietary supplements

Links

  • Content: A systematic review and meta-analysis examining how various supplements affect tumor progression in animal models, including data relevant to lipids found in shark liver oil.
  • Content: A study identifying specific alkylglycerols in shark liver oil that demonstrate anti-tumor activity in experimental settings.
  • Content: An article discussing how compounds from sharks may inhibit angiogenesis (the formation of new blood vessels) to starve tumors.
  • Content: A scoping review summarizing the evidence for shark liver oil’s ability to modulate the immune response and reduce inflammation.
  • Content: Research investigating the anti-angiogenic properties of analogues derived from shark liver oil components.
  • Content: An overview of various alternative approaches in cancer care, including the historical and anecdotal use of shark-derived products.

What you read on Jeg har Kræft is not a recommendation. Seek competent guidance.

About the Author & Professional Background

Portrætfoto af Hanne til forsiden.

This article has been prepared and validated by the undersigned, Hanne Kjær Uhlig. I am a registered nurse (1975, with clinical experience until 2013) and hold an M.Arch. (1983, specializing in industrial design), and I taught at DTU (Technical University of Denmark) for a number of years.

Following the loss of my mother to cancer in 2000 and my own cancer diagnosis in 2024, I founded this non-profit information site “Jeg har Kræft” (I Have Cancer).

The goal is to use my analytical and academic approach to bring clarity, safety, and scientific evidence to the field of integrative, complementary, and alternative cancer treatment. At the same time, my healthcare experience is utilized to make the articles patient-centered and relevant.

Article characteristics:

  • Clinical and personal background: Created from a combination of decades of experience as a nurse and personal experiences as both a patient and a relative.
  • Scientific methodology: The content is based on systematic research of medical databases and clinical trials. The articles are consistently supported by source references under Links.
  • Independent non-profit project: Operations are funded through voluntary donations and memberships through the Support Association Jeg har Kræft. The site is completely independent of commercial manufacturer interests and works solely to improve the quality of life for cancer patients.
  • The board of directors of the support association consists of:

Community: Join the Facebook group: Jeg har Kræft – Hvad kan jeg gøre? Danish Language only.

What you read on Jeg har Kræft is not a recommendation. Seek professional guidance.