{"id":36989,"date":"2026-05-09T11:12:11","date_gmt":"2026-05-09T10:12:11","guid":{"rendered":"https:\/\/jegharkraeft.dk\/?p=36989"},"modified":"2026-05-09T11:51:21","modified_gmt":"2026-05-09T10:51:21","slug":"coleys-toxins","status":"publish","type":"post","link":"https:\/\/jegharkraeft.dk\/en\/coleys-toxins\/","title":{"rendered":"Coley&#8217;s Toxins. Coley\u2019s Toxins. William Coley. History of immunotherapy. Fever therapy. Hyperthermia treatment. Coley\u2019s Fluid. Sarcoma treatment. TNF Tumor Necrosis Factor. CHIPSA Hospital."},"content":{"rendered":"\n<div class=\"wp-block-group alignfull is-style-section-5 has-contrast-color has-base-background-color has-text-color has-background has-link-color wp-elements-45cbd0b8eeee5446800c0c815eebf321 has-global-padding is-layout-constrained wp-block-group-is-layout-constrained is-style-section-5--2\" id=\"menu\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--50);padding-bottom:var(--wp--preset--spacing--50)\">\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-ca2dd60b wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-8e292ba59e2e62619cb6b45f1da933f0\"><span class=\"ez-toc-section\" id=\"Treatments\"><\/span><a href=\"https:\/\/jegharkraeft.dk\/en\/cancer-treatments-overview\/\"><\/a><a href=\"https:\/\/jegharkraeft.dk\/en\/cancer-treatments-overview\/\">Treatments<\/a><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<div class=\"wp-block-group has-custom-interne-links-color has-text-color has-link-color wp-elements-2736ac244db3f0bb8a313a4ecb211dc3 has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<h4 class=\"wp-block-heading has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-35f40f17f5132b8bd633e6d156d90f41\"><a href=\"https:\/\/jegharkraeft.dk\/en\/cancer-protocols\/\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-hvid-tekst-color\">Protokols for cancer <\/mark><\/a><\/h4>\n\n\n\n<ol class=\"wp-block-list\">\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-6d75eeace0b9e7bcb76ee41a6f76cb3c\"><a href=\"https:\/\/jegharkraeft.dk\/en\/thomas-seyfried-protocol\/\">The metabolic and data-driven<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-ab3adce68e38ab255dfe3288b62ddd51\"><a href=\"https:\/\/jegharkraeft.dk\/en\/jane-mc-lellands-protocol\/\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-hvid-tekst-color\">Repurposed drugs and medical combinations<\/mark><\/a>\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/jegharkraeft.dk\/en\/beljanski-protocol\/\">Beljanski Protocol (Pao Pereira &amp; extracts<\/a>)<\/li>\n\n\n\n<li><a href=\"https:\/\/jegharkraeft.dk\/en\/burt-berkson-protocol\/\">Burt Berkson (ALA\/ LDN)<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/jegharkraeft.dk\/en\/coc-protocol\/\">Care Oncology Clinic (COC \u2013 repurposed drugs)<\/a><\/li>\n\n\n\n<li class=\"has-custom-her-st-r-du-color has-text-color has-link-color wp-elements-a5c74ee74632f037d31862e0f108a62e\"><a href=\"#coleys-toxins\">Coley\u2019s Toxins (immunotherapy\/ fever) (scroll down)<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/jegharkraeft.dk\/en\/flccc-cancer-protocol\/\">FLCCC Cancer Protocol (Ivermectin and Mebendazole)<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/jegharkraeft.dk\/en\/?p=36927\">Jane McLelland (how to starve cancer)<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/jegharkraeft.dk\/en\/joe-tippens-protocol\/\">Joe Tippens (fenbendazole)<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/jegharkraeft.dk\/en\/rick-simpson-oil-protocol\/\">Rick Simpson Oil (RSO) Protocol (highly concentrated cannabis oil)<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/jegharkraeft.dk\/en\/riordan-protocol\/\">Riordan (IV C-vitamin)<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/jegharkraeft.dk\/en\/stanislaw-burzynski-protocol\/\">Stanislaw Burzynski (antineoplastons)<\/a><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-8e3e013adf37c689ed5a679510ccf0a2\"><a href=\"https:\/\/jegharkraeft.dk\/en\/bill-henderson-protocol\/\">Intensive diet and detoxification<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-cc2cfce90f24c4afed54b682c833dd83\"><a href=\"https:\/\/jegharkraeft.dk\/en\/valter-longo-protocol\/\">Strategic fasting<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-076a2c943f67124c371f7fd04f305ad9\"><a href=\"https:\/\/jegharkraeft.dk\/en\/mistelten-protocol\/\">Tradition and wisdom<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-fc3c8843b9bbcb9a0794ccc837b22275\"><a href=\"https:\/\/jegharkraeft.dk\/en\/german-new-medicine\/\">Mind-body and biological decoding<\/a><\/li>\n<\/ol>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img decoding=\"async\" src=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins8.jpg\" alt=\"Coleys Toxins symboliseret ved et h\u00e6tteglas med immunterapi holdt op mellem to fingre.\" class=\"wp-image-36980\" style=\"aspect-ratio:3\/2;object-fit:cover;width:550px\"\/><\/figure>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull is-style-default has-global-padding is-layout-constrained wp-container-core-group-is-layout-b040ace0 wp-block-group-is-layout-constrained has-background\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--60);padding-right:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--60);padding-left:var(--wp--preset--spacing--20);background-image:url(&apos;https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins8.jpg&apos;);background-position:44% 36%;background-size:cover;\">\n<div class=\"gb-element-906497af\">\n<h1 class=\"wp-block-heading\" id=\"coleys-toxins\"><span class=\"ez-toc-section\" id=\"Coleys_Toxins_%E2%80%93_Protocol_the_father_of_immunotherapy\"><\/span>Coley&#8217;s Toxins &#8211; Protocol (the father of immunotherapy)<span class=\"ez-toc-section-end\"><\/span><\/h1>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-custom-sort-tekst-color has-alpha-channel-opacity has-custom-sort-tekst-background-color has-background\"\/>\n\n\n\n<h4 class=\"wp-block-heading\">Summary of Coley&#8217;s Toxins<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Purpose:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>To induce a powerful, systemic immune response (fever) using bacterial toxins to get the body&#8217;s own defense to recognize and attack cancer cells.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Content:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Injections with a mixture of killed bacteria (<em>Streptococcus pyogenes<\/em> and <em>Serratia marcescens<\/em>). The treatment should induce chills and high fever (39-40\u00b0C) to be effective.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>The central idea:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Cancer cells often hide from the immune system (cold tumors).<br>By simulating a life-threatening infection, the immune system is forced into high gear, thereby (as a &#8220;side effect&#8221;\/extra effect) also attacking the tumor.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-custom-sort-tekst-color has-alpha-channel-opacity has-custom-sort-tekst-background-color has-background\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Who_was_Dr_William_Coley\"><\/span>Who was Dr. William Coley<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins10.jpg\" alt=\"Coleys Toxins symboliseret ved en l\u00e6ge der injiceret noget i armen p\u00e5 en mand, der sidder p\u00e5 en stol.\" class=\"wp-image-26745\" style=\"object-fit:cover;width:150px;height:150px\" srcset=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins10.jpg 1024w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins10-300x300.jpg 300w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins10-100x100.jpg 100w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins10-600x600.jpg 600w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins10-150x150.jpg 150w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins10-768x768.jpg 768w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">In 1890, long before chemotherapy and radiation became standard, the young surgeon William Coley worked at New York Cancer Hospital (today Memorial Sloan Kettering). He was frustrated by how often cancer returned, even after he had cut out the tumors.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The turning point came when he dove into the hospital&#8217;s archives and found a patient, Fred Stein, who seven years earlier had been given up with a large, inoperable tumor on his neck. Stein had during hospitalization gotten a severe skin infection (erysipelas) with high fever. When the infection subsided, the cancer node had miraculously disappeared. Coley tracked down Stein and found him alive and well.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This inspired Coley to deliberately infect patients with live bacteria. When this proved too dangerous, he developed a mixture of killed, heat-treated bacteria. The result became <em>Coley\u2019s Fluid<\/em> (later <em>Toxins<\/em>), with which he treated over 1,000 patients during his career \u2013 often with remarkable results, especially with sarcomas (bone and soft tissue cancer) [1, 8].<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Fever_as_a_weapon\"><\/span>Fever as a weapon<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins12.jpg\" alt=\"Coleys Toxins symboliseret ved en planche med et menneske til venstre og nogle virus og tumorceller til h\u00f8jre. Desuden vises en spr\u00f8jte med kanyle.\" class=\"wp-image-26747\" style=\"object-fit:cover;width:150px;height:150px\" srcset=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins12.jpg 1024w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins12-300x300.jpg 300w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins12-100x100.jpg 100w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins12-600x600.jpg 600w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins12-150x150.jpg 150w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins12-768x768.jpg 768w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Coley did not know exactly <em>why<\/em> it worked, but today we understand the biology. The treatment works via two primary mechanisms:<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">1. Hyperthermia (fever)<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Cancer cells are generally more heat-sensitive than healthy cells. When body temperature rises to 39-40 degrees during treatment, direct heat damage occurs to the tumor tissue [5].<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The fever also makes cell membranes more fluid, making cancer cells more vulnerable to the immune system&#8217;s attacks.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">2. Cytokine storm and TNF<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">The injection tricks the body into thinking it is under a massive bacterial attack. This triggers a cascade of signaling substances:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Macrophages and dendritic cells:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Are explosively activated. They begin to &#8220;eat&#8221; tissue perceived as foreign and present cancer antigens to the T cells.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Tumor necrosis factor (TNF):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>In 1975, researchers discovered a substance in the blood that caused tumors to die (necrosis). They called it TNF. It turned out that Coley&#8217;s toxins were one of the most potent ways to stimulate the body&#8217;s own production of TNF [6].<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Interleukins (IL-12, IL-2):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Substances that direct the &#8220;killer cells&#8221; toward the target.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">In short, the toxins transform a &#8220;cold&#8221; tumor (which the immune system ignores) into a &#8220;hot&#8221; tumor (which the immune system attacks), because the tumor suddenly finds itself in the middle of an inflammatory battlefield.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Why_did_the_treatment_disappear\"><\/span>Why did the treatment disappear<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins11.jpg\" alt=\"Coleys Toxins symboliseret ved nogle forskellige flasker med medicin, der st\u00e5r st\u00f8vede p\u00e5 en hylde.\" class=\"wp-image-26746\" style=\"object-fit:cover;width:150px;height:150px\" srcset=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins11.jpg 1024w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins11-300x300.jpg 300w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins11-100x100.jpg 100w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins11-600x600.jpg 600w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins11-150x150.jpg 150w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins11-768x768.jpg 768w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">If it was so effective, why don&#8217;t we use it today? The answer is complex and concerns the development of medical history:<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Inconsistency<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Coley made 15 different recipes in his lifetime. Some were potent, others did not work. It was difficult to standardize.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">The emergence of radiation and chemo<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">In the early 1900s, radiation therapy emerged. It was new, futuristic, and it worked the same every time (the tumor shrank). Doctors preferred this predictability over Coley&#8217;s unpredictable fever cures.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">FDA and the Thalidomide scandal<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">In 1962, the FDA tightened the rules for drugs. Coley&#8217;s toxins were classified as an &#8220;unproven drug&#8221; and lost their approval (<em>Grandfather status<\/em>), making it illegal to market in the USA.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"The_protocol_in_practice\"><\/span>The protocol in practice<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins7.jpg\" alt=\"Coleys Toxins symboliseret ved en sygeplejerske i bl\u00e5 uniform og en kvindelig patient der sider og modtager v\u00e6ske i drop.\" class=\"wp-image-26742\" style=\"object-fit:cover;width:150px;height:150px\" srcset=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins7.jpg 1024w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins7-300x300.jpg 300w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins7-100x100.jpg 100w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins7-600x600.jpg 600w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins7-150x150.jpg 150w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins7-768x768.jpg 768w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Today, the treatment is primarily offered at specialty clinics in Mexico (e.g., CHIPSA Hospital) or Germany, as it is not approved as standard treatment in most Western countries [4].<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">The process itself<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">The treatment is not pleasant. It is a cure that requires willpower.<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Injection:<\/strong>\n<ul class=\"wp-block-list\">\n<li>The patient receives a small dose of toxins (intravenously or directly into the tumor).<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>The reaction:<\/strong>\n<ul class=\"wp-block-list\">\n<li>Within an hour, the patient begins to shiver violently (chills). This lasts 30-60 minutes.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>The fever:<\/strong>\n<ul class=\"wp-block-list\">\n<li>Then the temperature rises quickly to 39-40 degrees. The patient lies with a high fever for 4-6 hours.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Completion:<\/strong>\n<ul class=\"wp-block-list\">\n<li>The fever subsides, and the patient is exhausted, but often pain-free (since TNF also acts as a painkiller).<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<h4 class=\"wp-block-heading\">Frequency and duration<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Coley insisted that the treatment should continue for a long time.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Frequency:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>2-3 times a week.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Duration:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>He recommended continuing treatment for up to 6 months after the tumor had disappeared, to kill microscopic remains. Many modern failures are due to stopping too early.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Modern_research_and_evidence\"><\/span>Modern research and evidence<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins9.jpg\" alt=\"Coleys Toxins symboliseret ved en mand i kittel, der kigger i et mikroskop. Bag dette st\u00e5r en pc-sk\u00e6rm.\" class=\"wp-image-26744\" style=\"object-fit:cover;width:150px;height:150px\" srcset=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins9.jpg 1024w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins9-300x300.jpg 300w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins9-100x100.jpg 100w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins9-600x600.jpg 600w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins9-150x150.jpg 150w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins9-768x768.jpg 768w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Coley\u2019s Toxins are considered the &#8220;grandfather of immunotherapy&#8221; today. Modern checkpoint inhibitors (such as Keytruda) are built on the same principle of activating the immune system, but they do it chemically and precisely, where Coley did it broadly and biologically.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">There are no large, modern phase 3 studies that meet today&#8217;s requirements. The evidence rests on:<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Historical data<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Coley&#8217;s own records show a 5-year survival of over 60% for inoperable sarcomas \u2013 numbers that are still difficult to match with modern chemo [2].<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Japan<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">In Japan, a modern variant called &#8220;Picibanil&#8221; (OK-432) is used, which is based on the same bacterial strain. It is approved for the treatment of certain cancer types [7].<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Spontaneous regression<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Research into &#8220;miraculous cures&#8221; shows that a very large proportion of patients who inexplicably recover from cancer without treatment have had a serious fever infection beforehand [3].<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Passive_heat_vs_active_fever\"><\/span>Passive heat vs. active fever<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"438\" height=\"432\" src=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins3.jpg\" alt=\"Coleys Toxins symboliseret ved et billede af en r\u00f8d viruspartikel.\" class=\"wp-image-26737\" style=\"object-fit:cover;width:150px;height:150px\" srcset=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins3.jpg 438w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins3-100x100.jpg 100w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins3-300x296.jpg 300w\" sizes=\"auto, (max-width: 438px) 100vw, 438px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">When reading about the effect of heat on cancer, it is natural to think that one can achieve the same effect at home with infrared blankets, saunas, or hot baths.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Here it is crucial to understand the difference between the three types of heat treatment:<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><a href=\"https:\/\/jegharkraeft.dk\/en\/saunataeppe\/\" target=\"_blank\" rel=\"noreferrer noopener\">Wellness heat (sauna\/ infrared blanket)<\/a><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">This is <strong>passive<\/strong> heating. The heat comes from outside and hits the skin. The body&#8217;s thermostat (in the brain) reacts immediately by trying to <em>cool<\/em> you down (you sweat, and blood vessels in the skin dilate).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Your core temperature rises only minimally, and most importantly: Your immune system &#8220;sleeps&#8221; on. It does not trigger the aggressive signaling substances (TNF and cytokines) that are necessary to kill cancer.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It is good for well-being and detoxification, but it is not cancer treatment.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><a href=\"https:\/\/jegharkraeft.dk\/en\/hypertermi\/\" target=\"_blank\" rel=\"noreferrer noopener\">Medical hyperthermia<\/a><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">This is done at clinics with advanced machines (microwaves or radio waves) that heat the tumor or the whole body from the outside, while the patient is often anesthetized.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Here, the core temperature is forced up to 40-42 degrees. This physically stresses the cancer cells, but it does not activate the immune system in the same &#8220;intelligent&#8221; way as an infection.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Also see <a href=\"https:\/\/jegharkraeft.dk\/en\/magnetisk-hypertermi\/\" target=\"_blank\" rel=\"noreferrer noopener\">Magnetic hyperthermia<\/a><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Active fever therapy (Coley\u2019s)<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Here the heat comes from within. The thermostat in the brain is turned up because the body thinks it is under attack. The heat is not the goal in itself, but a <em>byproduct<\/em> of a massive immunological armament.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It is the combination of the heat <em>and<\/em> the immune system&#8217;s &#8220;storm attack&#8221; that makes this method unique.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">An infrared sauna can never simulate this biological alarm state.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Important_warnings\"><\/span>Important warnings<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1280\" height=\"853\" src=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Vigtige-advarsler.jpg\" alt=\"Vigtige advarsler symboliseret ved et fuldt-stop skilt mod bl\u00e5 himmel.\" class=\"wp-image-26891\" style=\"object-fit:cover;width:150px;height:150px\" srcset=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Vigtige-advarsler.jpg 1280w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Vigtige-advarsler-600x400.jpg 600w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Vigtige-advarsler-300x200.jpg 300w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Vigtige-advarsler-1024x682.jpg 1024w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Vigtige-advarsler-768x512.jpg 768w\" sizes=\"auto, (max-width: 1280px) 100vw, 1280px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Since the treatment involves extremely high fever (40 degrees) and violent activation of the immune system, there are groups that cannot tolerate the treatment.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Brain metastases<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Patients with spread to the brain should <strong>not<\/strong> receive this treatment as a rule.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Why:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The powerful inflammation (inflammatory response) can cause tumors in the brain to swell. Since the skull cannot give way, the pressure in the brain increases, which can be life-threatening.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">Heart problems<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">The treatment pushes the pulse up and significantly stresses the circulation (like a marathon run).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Why:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>If you have a weak heart or serious cardiovascular disease, the strain from the high fever can lead to heart failure.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">Autoimmune diseases<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">This is a double-edged sword.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Why:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The treatment strongly activates the immune system. For some, this can trigger a flare-up of their autoimmune disease (e.g., rheumatoid arthritis or Crohn&#8217;s disease).<\/li>\n\n\n\n<li><strong>But:<\/strong> Historically, some of Dr. Coley&#8217;s patients experienced the opposite: That their autoimmune disease went into remission or disappeared because the immune system was &#8220;rebooted&#8221;.\n<ul class=\"wp-block-list\">\n<li>You should therefore not automatically rule out the treatment, but discuss the pros and cons with a specialist.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">Safety<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Always consult your healthcare provider before starting a protocol.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Conclusion\"><\/span>Conclusion<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1280\" height=\"1163\" src=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins2.webp\" alt=\"Coleys Toxins symboliseret ved silhuet af et hoved med gyldne farver.\" class=\"wp-image-26738\" style=\"object-fit:cover;width:150px;height:150px\" srcset=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins2.webp 1280w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins2-600x545.webp 600w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins2-300x273.webp 300w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins2-1024x930.webp 1024w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins2-768x698.webp 768w\" sizes=\"auto, (max-width: 1280px) 100vw, 1280px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Coley\u2019s Toxins represent a lost branch of medicine that prioritized the body&#8217;s own abilities over external chemistry. It is not a &#8220;magic cure&#8221; without costs. It is a physically demanding treatment that simulates serious illness to create health.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The method is most relevant for patients with sarcomas, lymphomas, or melanomas, and for those seeking a treatment that can be combined with immunotherapy or used when conventional options are exhausted.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">However, it requires travel abroad or participation in rare clinical trials.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Example_of_a_day_on_the_protocol\"><\/span>Example of a day on the protocol<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1280\" height=\"1280\" src=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins1.webp\" alt=\"Coleys Toxins symboliseret ved tegning af forskellige farver og st\u00f8rrelser af virus.\" class=\"wp-image-26739\" style=\"object-fit:cover;width:150px;height:150px\" srcset=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins1.webp 1280w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins1-300x300.webp 300w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins1-100x100.webp 100w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins1-600x600.webp 600w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins1-1024x1024.webp 1024w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins1-150x150.webp 150w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/12\/Coleys-Toxins1-768x768.webp 768w\" sizes=\"auto, (max-width: 1280px) 100vw, 1280px\" \/><\/figure>\n\n\n\n<h4 class=\"wp-block-heading\">A typical treatment day<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Receiving Coley\u2019s Toxins is not passive like receiving chemo, where you sit and read a magazine. It is hard physical work for the body. A treatment day typically goes like this:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Morning: Preparation<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The patient eats lightly, but nutritiously, and makes sure to be well-hydrated. One prepares mentally for the physical exertion that awaits. The body needs resources to produce heat.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Midday: The injection (&#8220;the starting shot&#8221;)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The doctor gives the injection (either into a vein or directly into the skin near the tumor). The dose is carefully adjusted based on the previous treatment&#8217;s reaction. The goal is to hit exactly the amount that triggers fever, without it becoming dangerous.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Afternoon: The chill phase (&#8220;the chill&#8221;)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>About 45-60 minutes after the injection, the body reacts. It does not start with heat, but with violent chills. The patient freezes and shivers uncontrollably, like with a severe flu. This typically lasts 30-45 minutes. Here, the patient is wrapped in warm blankets and monitored closely.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Late afternoon: The fever phase (&#8220;the working phase&#8221;)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The shivering stops, and the heat sets in. The temperature rises quickly to 39-40 degrees. This is where the therapeutic work happens. The immune system is at its peak, and the heat stresses the cancer cells.<\/li>\n\n\n\n<li>The patient is often drowsy, but conscious. Hot drinks are consumed to support the fever. This condition is typically maintained for 3-6 hours.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Evening: Lysis and rest<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The fever subsides, often accompanied by profuse sweating. Many patients then experience a paradoxical feeling of well-being, mental clarity, and pain relief (since cytokines also act as painkillers). The rest of the evening and night is spent on deep, restorative sleep.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>The next day<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"coleys-toxins\">One is tired, as after a bout of flu, but often has a good appetite. The day is spent resting until the next treatment typically follows 2-3 days later.<\/p>\n\n\n\n<p class=\"has-custom-menu-links-color has-text-color has-link-color wp-elements-485790e51077e9636b3d4b79d3c87ead wp-block-paragraph\"><a href=\"#menu\">(to menu)<\/a><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Links<\/h4>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-92712585031293bb2225df4ce288dc06 wp-block-paragraph\">[1] <a href=\"https:\/\/www.mskcc.org\/timeline\/immunotherapy-msk\" target=\"_blank\" rel=\"noreferrer noopener\">MSK Immunotherapy \u2014 Timeline of Progress<\/a> (Memorial Sloan Kettering Cancer Center, undated)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Content:<\/strong> A timeline from one of the world&#8217;s leading cancer hospitals that recognizes William Coley as &#8220;The Father of Immunotherapy&#8221; (1893) and describes how his work led directly to the discovery of TNF (Tumor Necrosis Factor).<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-c05c76fa30ab80de96b875bcc0ff98c0 wp-block-paragraph\">[2] <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1888599\/\" target=\"_blank\" rel=\"noreferrer noopener\">The Toxins of William B. Coley and the Treatment of Bone and Soft-Tissue Sarcomas<\/a> (PubMed \/ Iowa Orthop J, 2006)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Content:<\/strong> A peer-reviewed medical article that objectively analyzes Coley&#8217;s data. The author concludes that the results for soft tissue sarcomas were comparable to or better than modern treatments.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-dad4283980d38f775c7f0d2b221b3865 wp-block-paragraph\">[3] <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3312698\/\" target=\"_blank\" rel=\"noreferrer noopener\">Immunity over inability: The spontaneous regression of cancer<\/a> (PMC \/ PubMed, 2011)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Content:<\/strong> A scientific article that replaces the book link. It reviews the phenomenon of &#8220;spontaneous regression&#8221; and confirms that acute infections (fever) historically have played a key role in cases where cancer disappears on its own.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-6cf9952504cf75da9c8410ef1d9f1574 wp-block-paragraph\">[4] <a href=\"https:\/\/hufeland.com\/en\/concept\/naturopathy\/fever-therapy\/fever-therapy-details\" target=\"_blank\" rel=\"noreferrer noopener\">Details and background: Fever therapy<\/a> (Hufeland Klinik)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Content:<\/strong> The Hufeland Clinic in Germany is one of the few places in Europe that continues Coley&#8217;s legacy. The page explains the concept of &#8220;Active Fever Therapy,&#8221; where biological agents are used to force the body&#8217;s temperature up from within, which differs from passive heating from the outside.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-ff1dc6f744ccc3cd4ece12815586af48 wp-block-paragraph\">[5] <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4861392\/\" target=\"_blank\" rel=\"noreferrer noopener\">Hyperthermia: How Can It Be Used?<\/a> (PubMed, National Cancer Institute \/ PMC, 2016)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Content:<\/strong> An overview of how heat (hyperthermia) is used in modern cancer treatment. The article confirms the principle that high temperatures can damage cancer cells and make them more susceptible to treatment.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-5af9a7be79c008215e7fa4d05b644d2d wp-block-paragraph\">[6] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7724661\/\" target=\"_blank\" rel=\"noreferrer noopener\">Coley&#8217;s toxins, tumor necrosis factor and cancer research<\/a> (PubMed, 1994\/ 2016)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Content:<\/strong> This is the abstract of the historical review that directly links Coley&#8217;s toxins to the discovery of cytokines and TNF. It explains the biological mechanism that Coley unknowingly exploited.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-ed1aa6216ff73620d692bb29088d3633 wp-block-paragraph\">[7] <a href=\"https:\/\/ar.iiarjournals.org\/content\/anticanres\/24\/5C\/3295.full.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Biological Effect of OK-432 (Picibanil)<\/a> (Anticancer Research, PDF, 2004)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Content:<\/strong> An article about the Japanese drug OK-432, which is a modern, standardized version of Coley&#8217;s principle. It shows that the method is recognized and used in parts of the world today.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-db6b760f987200aec648ab804470dc92 wp-block-paragraph\">[8] <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11466495\/\" target=\"_blank\" rel=\"noreferrer noopener\">William Coley: The Pioneer and the Father of Immunotherapy<\/a> (PMC, NIH, 2024)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Content:<\/strong> A brand new article (2024) that summarizes Coley&#8217;s life&#8217;s work and argues that his ideas were ahead of their time and form the basis for today&#8217;s immunotherapy.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-fc4c533bc3c062cee242964569783159 wp-block-paragraph\"><strong>Page created:<\/strong> December 19, 2025<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-menu-links-color\">\u2764<\/mark><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>What you read on &#8220;Jeg har Kr\u00e6ft&#8221; is not a recommendation. Seek competent guidance.<\/em><\/strong><\/p>\n<\/div>\n<\/div>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Indhold<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/jegharkraeft.dk\/en\/coleys-toxins\/#Treatments\" >Treatments<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/jegharkraeft.dk\/en\/coleys-toxins\/#Coleys_Toxins_%E2%80%93_Protocol_the_father_of_immunotherapy\" >Coley&#8217;s Toxins &#8211; Protocol (the father of immunotherapy)<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/jegharkraeft.dk\/en\/coleys-toxins\/#Who_was_Dr_William_Coley\" >Who was Dr. William Coley<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/jegharkraeft.dk\/en\/coleys-toxins\/#Fever_as_a_weapon\" >Fever as a weapon<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/jegharkraeft.dk\/en\/coleys-toxins\/#Why_did_the_treatment_disappear\" >Why did the treatment disappear<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/jegharkraeft.dk\/en\/coleys-toxins\/#The_protocol_in_practice\" >The protocol in practice<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/jegharkraeft.dk\/en\/coleys-toxins\/#Modern_research_and_evidence\" >Modern research and evidence<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/jegharkraeft.dk\/en\/coleys-toxins\/#Passive_heat_vs_active_fever\" >Passive heat vs. active fever<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/jegharkraeft.dk\/en\/coleys-toxins\/#Important_warnings\" >Important warnings<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/jegharkraeft.dk\/en\/coleys-toxins\/#Conclusion\" >Conclusion<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/jegharkraeft.dk\/en\/coleys-toxins\/#Example_of_a_day_on_the_protocol\" >Example of a day on the protocol<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Treatments Protokols for cancer Coley&#8217;s Toxins &#8211; Protocol (the father of immunotherapy) Summary of Coley&#8217;s Toxins Purpose: Content: The central idea: Who was Dr. William Coley In 1890, long before chemotherapy and radiation became standard, the young surgeon William Coley worked at New York Cancer Hospital (today Memorial Sloan Kettering). He was frustrated by how [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[392,374],"tags":[],"class_list":["post-36989","post","type-post","status-publish","format-standard","hentry","category-protocols","category-treatments"],"modified_by":"Hanne Kj\u00e6r Uhlig","wpml_current_locale":"en_US","wpml_translations":[],"_links":{"self":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts\/36989","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/comments?post=36989"}],"version-history":[{"count":3,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts\/36989\/revisions"}],"predecessor-version":[{"id":37032,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts\/36989\/revisions\/37032"}],"wp:attachment":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/media?parent=36989"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/categories?post=36989"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/tags?post=36989"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}