{"id":35144,"date":"2026-04-28T18:14:14","date_gmt":"2026-04-28T17:14:14","guid":{"rendered":"https:\/\/jegharkraeft.dk\/?p=35144"},"modified":"2026-05-02T21:00:11","modified_gmt":"2026-05-02T20:00:11","slug":"pomegranate","status":"publish","type":"post","link":"https:\/\/jegharkraeft.dk\/en\/pomegranate\/","title":{"rendered":"Pomegranate and cancer"},"content":{"rendered":"\n<div class=\"wp-block-group alignfull is-style-section-5 has-contrast-color has-base-background-color has-text-color has-background has-link-color wp-elements-349dd8bf18729f3aa565438b5f0385c2 has-global-padding is-layout-constrained wp-block-group-is-layout-constrained is-style-section-5--2\" id=\"menu\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--50);padding-bottom:var(--wp--preset--spacing--50)\">\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-ca2dd60b wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-a867a5e69af727a1b962d2b1d75fb9e7\"><span class=\"ez-toc-section\" id=\"Dietary_Supplements_Grouped_by_Effect\"><\/span><a href=\"https:\/\/jegharkraeft.dk\/en\/kosttilskud-grupperet\/\"><\/a><a href=\"https:\/\/jegharkraeft.dk\/en\/kosttilskud-grupperet\/\">Dietary Supplements Grouped by Effect<\/a><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Dietary_Supplements_Alphabetical\"><\/span><a href=\"https:\/\/jegharkraeft.dk\/en\/supplements-alphabetically\/\">Dietary Supplements Alphabetical<\/a><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h4 class=\"wp-block-heading has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-a441de5ff5d5b6faf33aaf9c53fc3841\"><a href=\"https:\/\/jegharkraeft.dk\/en\/acai-berries-and-cancer\/\">A,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/baicalin\/\"> B,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/cats-claw-tomentosa\/\"> C,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/danshen\/\">D,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/echinacea\/\"> E+F,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/garcinia-cambogia\/\"> G,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/shark-liver-oil\/\"> H,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/ingefaer\/\"> I+J+K,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/lions-mane\/\"> L,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/maitake\/\"> M,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/n-acetyl-cysteine\/\"> N,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/omega-3\/\"> O,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/peppermint\/pebermynte\/\"> <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-hvid-tekst-color\">P<\/mark><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-interne-links-color\">,<\/mark><\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/quercetin\/\"> Q,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/reishi\/\"> R,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/selenium\/\"> S,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/thc-cannabis\/\"> T,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/vitamin-b\/\"> U+V+Z<\/a><\/h4>\n\n\n\n<ul class=\"wp-block-list has-custom-hvid-tekst-color has-text-color has-link-color wp-elements-c31d9ad9b4376dd708e7cb9582e8c1eb\">\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-21d13b8dd193f5f3fc44511747e3aae4\"><a href=\"https:\/\/jegharkraeft.dk\/en\/ginseng\/\">Panax ginseng<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-6d2b3922918787a3b62d6b91c5e9edd1\"><a href=\"https:\/\/jegharkraeft.dk\/en\/papaya-extract\/\">Papaya leaf extract<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-3d37347a99daa83d9d196fbce1835f21\"><a href=\"https:\/\/jegharkraeft.dk\/en\/pau-darco\/\">Pau D&#8217;Arco<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-9695fe2fdff287917c6cee892c3f1384\"><a href=\"https:\/\/jegharkraeft.dk\/en\/pao-pereira\/\">Pao Pereira<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-99dc54dfc7d315a4bfd08405eeb913ca\"><a href=\"https:\/\/jegharkraeft.dk\/en\/peppermint\/\">Peppermint<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-709db9f5a2601fd41ce9b84bc08ff17b\"><a href=\"https:\/\/jegharkraeft.dk\/en\/st-johns-wort\/\">St. John&#8217;s Wort<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-e02036725c9fb7625fec090ed2df67bf\"><a href=\"https:\/\/jegharkraeft.dk\/en\/phlorizin\/\">Phlorizin<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-14046cc547feec6b1114c2f69ccecda4\"><a href=\"https:\/\/jegharkraeft.dk\/en\/phosphatidylcholine\/\">Phosphatidylcholine (PC)<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-dcdd4250f942d2884bb1b366a0643a2c\"><a href=\"https:\/\/jegharkraeft.dk\/en\/piperine\/\">Piperine<\/a><\/li>\n\n\n\n<li class=\"has-custom-her-st-r-du-color has-text-color has-link-color wp-elements-720fb3c3f9c9d9934b3161997bf70749\"><a href=\"#pomegranate\">Pomegranate (scroll down)<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-428c958433b81c3703f5f4cc95bb1ade\"><a href=\"https:\/\/jegharkraeft.dk\/en\/poria-cocos\/\">Poria cocos (medicinal mushroom)<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-0c77601a35c73481066a46d129005a8e\"><a href=\"https:\/\/jegharkraeft.dk\/en\/proanthocyanidins\/\">Proanthocyanidins<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-3d1f43d6714f6a91f4fd6ecc14f19927\"><a href=\"https:\/\/jegharkraeft.dk\/en\/proline\/\">Proline<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-b3b0f469201b87e05d1d6d5bb30f16e3\"><a href=\"https:\/\/jegharkraeft.dk\/en\/propolis\/\">Propolis<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-65868207f1a69bff4a13f901c2a427a7\"><a href=\"https:\/\/jegharkraeft.dk\/en\/pycnogenol\/\">Pycnogenol<\/a><\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"650\" height=\"650\" src=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bpomegranat-granataeble.jpg\" alt=\"Granat\u00e6ble i gr\u00f8nt pilleglas fra Swanson med p\u00e5skriften Pomegranate Extract.\" class=\"wp-image-35143\" style=\"aspect-ratio:3\/2;object-fit:cover;width:550px\" srcset=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bpomegranat-granataeble.jpg 650w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bpomegranat-granataeble-300x300.jpg 300w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bpomegranat-granataeble-100x100.jpg 100w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bpomegranat-granataeble-600x600.jpg 600w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bpomegranat-granataeble-150x150.jpg 150w\" sizes=\"auto, (max-width: 650px) 100vw, 650px\" \/><\/figure>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull is-style-default has-global-padding is-layout-constrained wp-container-core-group-is-layout-b040ace0 wp-block-group-is-layout-constrained has-background\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--60);padding-right:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--60);padding-left:var(--wp--preset--spacing--20);background-image:url(&apos;http:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bpomegranat-granataeble.jpg&apos;);background-position:44% 36%;background-size:cover;\">\n<div class=\"gb-element-906497af\">\n<h1 class=\"wp-block-heading\" id=\"pomegranate\"><span class=\"ez-toc-section\" id=\"Pomegranate_and_cancer\"><\/span>Pomegranate and cancer<span class=\"ez-toc-section-end\"><\/span><\/h1>\n\n\n\n<h4 class=\"wp-block-heading\">What is pomegranate<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Pomegranate (<em>Punica granatum<\/em>) is a fruit about the size of an orange with a tough, reddish-brown skin. Inside are hundreds of small, juicy, red seeds with a sweet, tart, and slightly bitter taste. The seeds are surrounded by a whitish membrane that is bitter and should not be eaten. Pomegranate is not only tasty but also packed with antioxidants, vitamins, and minerals that can have beneficial effects on health.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Use_of_pomegranate\"><\/span>Use of pomegranate<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Pomegranate has been valued for centuries for its taste and symbolic significance. But beyond being a culinary delicacy, pomegranate also contains a wealth of bioactive compounds with the potential to influence human health, including in the fight against cancer.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Mechanisms_of_action_and_potential_in_cancer\"><\/span>Mechanisms of action and potential in cancer<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Pomegranate is a rich source of antioxidants, especially polyphenols such as ellagic acid, punicalagins, and anthocyanins. These substances have shown a range of potentially beneficial effects in relation to cancer:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Inhibition of cancer cell division<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In laboratory experiments, pomegranate extract has been shown to inhibit the proliferation (cell division) of various cancer cell types, including breast, prostate, lung, and colon cancer [4, 5, 6].<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Induction of apoptosis<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Pomegranate can trigger programmed cell death (apoptosis) in cancer cells, which is a natural process by which the body removes damaged or abnormal cells [3, 5].<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Anti-angiogenesis<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Pomegranate extract can inhibit the formation of new blood vessels (angiogenesis), which is crucial for the growth and spread of cancerous tumors [7].<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Anti-inflammatory effect<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Chronic inflammation can contribute to cancer development. Pomegranate has anti-inflammatory properties that can counteract this. The polyphenols in pomegranate possess these anti-inflammatory qualities, which can dampen inflammation in the body.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Increased sensitivity to chemotherapy<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Some studies suggest that pomegranate can increase the sensitivity of cancer cells to chemotherapy, potentially improving treatment effectiveness.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Strengthens the immune system<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Prebiotic effect:<\/strong> The ellagitannins in pomegranate act as prebiotics that nourish beneficial gut bacteria. This promotes the growth of &#8220;good&#8221; bacteria like <em>Bifidobacteria<\/em> and <em>Lactobacillus<\/em>, while inhibiting the growth of &#8220;bad&#8221; bacteria [1].<\/li>\n\n\n\n<li><strong>Increased diversity:<\/strong> A healthy gut flora is characterized by a high diversity of bacteria. Pomegranate contributes to increasing this diversity.<\/li>\n\n\n\n<li><strong>Stronger intestinal barrier:<\/strong> A healthy gut flora strengthens the intestinal barrier, preventing harmful substances from entering the body.<\/li>\n\n\n\n<li><strong>Increased production of immune cells:<\/strong> The gut houses a large portion of the body&#8217;s immune cells. A healthy gut flora stimulates the production of these cells and thus strengthens the immune defense [1].<\/li>\n\n\n\n<li><strong>Regulation of immune response:<\/strong> The gut flora plays a role in regulating the body&#8217;s immune response and preventing overreactions.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Advantages_of_pomegranate\"><\/span>Advantages of pomegranate<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">In addition to the positive effects of pomegranates, there are further advantages to its use as a supplementary treatment for cancer:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Enhances chemo and radiation<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Potential synergistic effect with conventional treatment:<\/strong> Some studies indicate that pomegranate can enhance the effect of chemotherapy and radiation therapy, potentially leading to better treatment outcomes.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Can improve quality of life<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Cancer and cancer treatment can lead to a range of side effects, such as fatigue, nausea, and loss of appetite. Pomegranate can potentially alleviate some of these symptoms and improve the quality of life for patients [9].<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Can protect healthy cells<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Cancer treatment can damage both cancer cells and healthy cells. In some studies, pomegranate extract has been shown to protect healthy cells from damage caused by chemotherapy and radiation therapy.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Can inhibit cancer metastasis<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The spread of cancer to other parts of the body (metastasis) is a serious complication. Some studies suggest that pomegranate can inhibit the metastatic process [4].<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Can support the immune system<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>A strong immune system is important in the fight against cancer. Pomegranate contains substances that can strengthen the immune system and increase the body&#8217;s ability to fight cancer cells [1].<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Natural and generally well-tolerated<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Can contribute to a healthy and varied diet.<\/li>\n\n\n\n<li>Can have positive effects on other health aspects, such as cardiovascular health and inflammation.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Disadvantages_and_limitations\"><\/span>Disadvantages and limitations<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Limited clinical evidence for the effect on cancer in humans.<\/li>\n\n\n\n<li>Interactions with medication are possible, especially blood thinners.<\/li>\n\n\n\n<li>Can cause stomach problems in some individuals.<\/li>\n\n\n\n<li>Not a substitute for conventional cancer treatment.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Interactions\"><\/span>Interactions<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">There are some forms of medication where there may be a potential risk of interaction with pomegranate:<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">1. Certain types of chemotherapy<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Pomegranate contains antioxidants. There is a theoretical concern that high doses of antioxidants could interfere with certain forms of chemotherapy that work by producing free radicals to destroy cancer cells. Although research in this area is complex and not conclusive, caution is advisable.<\/li>\n\n\n\n<li>Specific chemotherapeutic agents where interactions have been studied (primarily in laboratory studies) include <strong>cisplatin, doxorubicin, and vincristine.<\/strong> It is important to emphasize that the clinical relevance of these <em>in vitro<\/em> studies is not always clear.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">2. Hormone therapy<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Certain types of cancer, such as breast and prostate cancer, are treated with hormone therapy. Pomegranate contains substances that have shown anti-estrogenic effects in the lab and can influence hormone levels.<\/li>\n\n\n\n<li>There is a potential risk that pomegranate could interact with hormone treatments such as <strong>tamoxifen (for breast cancer) and aromatase inhibitors.<\/strong> Again, the clinical significance in humans is not fully clarified, but caution is necessary.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">3. Blood thinners (Anticoagulants)<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Pomegranate can potentially affect blood coagulation. There are reports of interactions between pomegranate juice and <strong>warfarin<\/strong>, where pomegranate could potentially increase the effect of warfarin and thus increase the risk of bleeding. Patients taking warfarin should be particularly cautious and consult their doctor if they wish to consume pomegranate products regularly.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">4. Medication metabolized by liver enzymes (Cytochrome P450 system)<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Pomegranate juice can inhibit certain enzymes in the liver, especially <strong>CYP3A4, CYP2C9, and CYP2D6<\/strong>, which are involved in the metabolism of many drugs, including certain forms of chemotherapy and pain medication. Inhibition of these enzymes can lead to increased concentrations of the medicine in the blood, potentially increasing the risk of side effects.<\/li>\n\n\n\n<li>Examples of medications metabolized by these enzymes are many, and it is important to discuss your specific medication list with your doctor.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">5. Blood pressure medication<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>There are some indications that pomegranate can lower blood pressure. While this can be beneficial in some cases, it can potentially enhance the effect of blood pressure medication and lead to excessively low blood pressure (hypotension).<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">Important points<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>This list is not exhaustive.<\/strong> There may be other interactions that are not yet fully understood.<\/li>\n\n\n\n<li><strong>The strength of the interaction can vary<\/strong> depending on the dose of pomegranate, the specific medication, and the individual patient&#8217;s metabolism.<\/li>\n\n\n\n<li><strong>Most reported interactions come from case reports or <em>in vitro<\/em> studies.<\/strong> More research in humans is needed to determine the clinical significance of many of these potential interactions.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Advice for cancer patients considering pomegranate:<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Clinical_trials\"><\/span>Clinical trials<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Although laboratory experiments have shown promising results, the clinical evidence for pomegranate&#8217;s effect on cancer in humans is still limited. Some smaller studies have indicated positive effects, e.g., on PSA levels in men with prostate cancer [8, 9] and on survival rates in patients with lung cancer.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">However, there is a need for more large-scale, randomized clinical trials to confirm these findings and establish the optimal dosage and use of pomegranate in cancer treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Dispensing_and_consumption\"><\/span>Dispensing and consumption<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Pomegranate can be consumed in various ways:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Fresh fruit<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Eat the seeds directly or use them in salads, smoothies, or desserts.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Juice<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Drink freshly squeezed pomegranate juice. Be aware of the sugar content in commercial juices.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Extract<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Pomegranate extract is available as a dietary supplement in capsule or powder form.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Conclusion\"><\/span>Conclusion<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Pomegranate is an exciting fruit with potential in the fight against cancer. Laboratory experiments have shown promising results, but more research is needed to confirm the effect in humans. Pomegranate can be a valuable supplement to a healthy lifestyle and conventional cancer treatment but should always be used in consultation with a competent practitioner.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Back to <a target=\"_blank\" rel=\"noreferrer noopener\" href=\"https:\/\/jegharkraeft.dk\/en\/supplements-alphabetically\/\">Dietary supplements<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"pomegranate\">See also <a target=\"_blank\" rel=\"noreferrer noopener\" href=\"https:\/\/jegharkraeft.dk\/en\/ellagic-acid\/\">Ellagic acid<\/a><\/p>\n\n\n\n<p class=\"has-custom-menu-links-color has-text-color has-link-color wp-elements-9190cfe395c28e4d2ec89873338ddaa5 wp-block-paragraph\"><a href=\"#menu\">(to menu)<\/a><a href=\"https:\/\/jegharkraeft.dk\/en\/supplements-alphabetically\/\"><\/a><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Links<\/h4>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-f01b6aef938a030b922be756e3e5daf3 wp-block-paragraph\">[1] <a href=\"https:\/\/nyhedscentrum.dk\/granataebler-booster-immunsystemet-og-kraeftbekaempende-t-celler-viser-tysk-studie\/\" target=\"_blank\" rel=\"noreferrer noopener\">Pomegranates boost the immune system and cancer-fighting T-cells, German study shows<\/a> (Nyhedscentrum, 2022) <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Content: An article describing a study where pomegranate components were found to enhance the activity of T-cells against cancer.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-bfaf8302fae692648ee8e901ffbb2451 wp-block-paragraph\">[2] <a href=\"https:\/\/www.propa.dk\/wp-content\/uploads\/2020\/02\/3371948_Propanyt-01-2020_KOST-og-PCA.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Diet and prostate cancer<\/a> (PROPA, Prostate Cancer Association, 2020) <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Content: A guide discussing the role of nutrition, including pomegranate, in managing prostate cancer.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-e5e02a4ddbf22682378a8284df87c3fe wp-block-paragraph\">[3] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39781712\/\" target=\"_blank\" rel=\"noreferrer noopener\">Biomimetic Fe3O4 Nanozymes Promote Apoptosis in Breast Cancer Cell Lines via Free Radical Scavenging and Inhibition of RelA\/p65<\/a> (PubMed, 2025) <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Content: A study on advanced delivery systems using pomegranate-related research to trigger cell death in breast cancer.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-52b52093c31ff599ba2a7b941078e07f wp-block-paragraph\">[4] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39521813\/\" target=\"_blank\" rel=\"noreferrer noopener\">Anticancer effects of pomegranate-derived peptide PG2 on CDK2 and miRNA-339-5p-mediated apoptosis via extracellular vesicles in acute leukemia<\/a> (PubMed, 2024) <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Content: Research investigating specific pomegranate peptides and their ability to induce apoptosis in leukemia cells.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-50a3ea74345292bc601f5ea3c2c1d854 wp-block-paragraph\">[5] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39611921\/\" target=\"_blank\" rel=\"noreferrer noopener\">Induction of Apoptosis and Antiproliferative Activity of MCF-7 Human Breast Cancer Cells with Sonicated Aqueous Peel Extract of Punica granatum L.<\/a> (PubMed, 2024) <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Content: An <em>in vitro<\/em> study showing how pomegranate peel extract inhibits the growth of breast cancer cells.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-b5900ace56e8fd6db072886df0e330cb wp-block-paragraph\">[6] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39235507\/\" target=\"_blank\" rel=\"noreferrer noopener\">Pomegranate Peel Extract as 6-Phosphogluconate Dehydrogenase (6PGD) Inhibitor for Treatment of Breast Cancer<\/a> (PubMed, 2025) <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Content: Research identifying pomegranate extract as an inhibitor of an enzyme critical for breast cancer cell metabolism.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-f8aa7db791a7a1e8b49dcbcf065521bd wp-block-paragraph\">[7] <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4200766\/#ijms-15-14949-f003\" target=\"_blank\" rel=\"noreferrer noopener\">Pomegranate and Its Components as Alternative Treatment for Prostate Cancer<\/a> (PubMed, 2014) <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Content: A comprehensive review of pomegranate&#8217;s role in inhibiting pathways relevant to prostate cancer progression.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-ca9d3ed5eb531286100e3821a5e6b8f5 wp-block-paragraph\">[8] <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4020278\/\" target=\"_blank\" rel=\"noreferrer noopener\">A double-blind, placebo-controlled randomised trial evaluating the effect of a polyphenol-rich whole food supplement on PSA progression in men with prostate cancer\u2014the UK NCRN Pomi-T study<\/a> (PubMed, 2014) <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Content: A randomized trial (phase 2) showing that a supplement containing pomegranate significantly reduced the rate of PSA rise in men with prostate cancer.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-4a934af451d7a5d7ec76bb1ad31e03ac wp-block-paragraph\">[9] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16818701\/\" target=\"_blank\" rel=\"noreferrer noopener\">Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer<\/a> (PubMed, 2006) <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Content: A clinical trial (phase 2) investigating the effect of pomegranate juice on PSA doubling time in prostate cancer patients.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-7833e375e46c47c88df67c7da1d2f80a wp-block-paragraph\"><strong>Page created:<\/strong> Jan 11, 2025. <strong>Last revised:<\/strong> Apr 28, 2026.<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-menu-links-color\">\u2764<\/mark><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>What you read on Jeg har Kr\u00e6ft is not a recommendation. Seek competent guidance.<\/em><\/strong><\/p>\n<\/div>\n<\/div>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_86 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Indhold<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/jegharkraeft.dk\/en\/pomegranate\/#Dietary_Supplements_Grouped_by_Effect\" >Dietary Supplements Grouped by Effect<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/jegharkraeft.dk\/en\/pomegranate\/#Dietary_Supplements_Alphabetical\" >Dietary Supplements Alphabetical<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/jegharkraeft.dk\/en\/pomegranate\/#Pomegranate_and_cancer\" >Pomegranate and cancer<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/jegharkraeft.dk\/en\/pomegranate\/#Use_of_pomegranate\" >Use of pomegranate<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/jegharkraeft.dk\/en\/pomegranate\/#Mechanisms_of_action_and_potential_in_cancer\" >Mechanisms of action and potential in cancer<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/jegharkraeft.dk\/en\/pomegranate\/#Advantages_of_pomegranate\" >Advantages of pomegranate<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/jegharkraeft.dk\/en\/pomegranate\/#Disadvantages_and_limitations\" >Disadvantages and limitations<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/jegharkraeft.dk\/en\/pomegranate\/#Interactions\" >Interactions<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/jegharkraeft.dk\/en\/pomegranate\/#Clinical_trials\" >Clinical trials<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/jegharkraeft.dk\/en\/pomegranate\/#Dispensing_and_consumption\" >Dispensing and consumption<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/jegharkraeft.dk\/en\/pomegranate\/#Conclusion\" >Conclusion<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Dietary Supplements Grouped by Effect Dietary Supplements Alphabetical A,. B,. C,. D,. E+F,. G,. H,. I+J+K,. L,. M,. N,. O,. P,. Q,. R,. S,. T,. U+V+Z Pomegranate and cancer What is pomegranate Pomegranate (Punica granatum) is a fruit about the size of an orange with a tough, reddish-brown skin. Inside are hundreds of small, juicy, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":35143,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[389,375,374],"tags":[],"class_list":["post-35144","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-supplements","category-alternative-treatments","category-treatments"],"modified_by":"Hanne Kj\u00e6r Uhlig","wpml_current_locale":"en_US","wpml_translations":[],"_links":{"self":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts\/35144","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/comments?post=35144"}],"version-history":[{"count":3,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts\/35144\/revisions"}],"predecessor-version":[{"id":36031,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts\/35144\/revisions\/36031"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/media\/35143"}],"wp:attachment":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/media?parent=35144"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/categories?post=35144"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/tags?post=35144"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}