{"id":32944,"date":"2025-03-21T19:25:38","date_gmt":"2025-03-21T18:25:38","guid":{"rendered":"https:\/\/jegharkraeft.dk\/?p=32944"},"modified":"2026-04-11T18:55:46","modified_gmt":"2026-04-11T17:55:46","slug":"nsaid-against-cancer","status":"publish","type":"post","link":"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/","title":{"rendered":"NSAID (non-steroidal anti-inflammatory drugs) and cancer"},"content":{"rendered":"\n<div class=\"wp-block-group alignfull is-style-section-5 has-contrast-color has-base-background-color has-text-color has-background has-link-color wp-elements-6f75bcf8d462b1cc332c4b71a91dd89a has-global-padding is-layout-constrained wp-block-group-is-layout-constrained is-style-section-5--2\" id=\"menu\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--50);padding-bottom:var(--wp--preset--spacing--50)\">\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-ca2dd60b wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-85c9ab605a9af581478ba1bfba8fd611\"><span class=\"ez-toc-section\" id=\"Treatments\"><\/span><a href=\"https:\/\/jegharkraeft.dk\/en\/cancer-treatments-overview\/\">Treatments<\/a><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-52532d4beacf4a32227a79286a8276fc\"><span class=\"ez-toc-section\" id=\"Complementary_and_Alternative_Treatments\"><\/span><a href=\"https:\/\/jegharkraeft.dk\/en\/alternative-cancer-treatments-overview\/\">Complementary and Alternative Treatments<\/a><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<div class=\"wp-block-group has-custom-interne-links-color has-text-color has-link-color wp-elements-1cd577ebc9dc7518ed4d830e395ce09c has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<ol class=\"wp-block-list\">\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-7307341993bac5ff4102b4d89cee9507\"><a href=\"https:\/\/jegharkraeft.dk\/en\/akupunktur\/\">Physical treatments<\/a>\n<ul class=\"wp-block-list\">\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-21ecdf12c111625993dc78232c60e9ad\"><a href=\"https:\/\/jegharkraeft.dk\/en\/repurposed-drugs\/\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-hvid-tekst-color\">Repurposed Drugs &#8211; General<\/mark><\/a>\n<ol class=\"wp-block-list\">\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-71238b14b3ec967697cef8d0eba2f45e\"><a href=\"https:\/\/jegharkraeft.dk\/en\/aspirin\/\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-hvid-tekst-color\">Painkillers and anti-inflammatory drugs<\/mark><\/a>\n<ul class=\"wp-block-list\">\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-a8a06d6d6717f6b088349d66369c07d1\"><a href=\"https:\/\/jegharkraeft.dk\/en\/aspirin\/\">Aspirin (low-dose acetylsalicylic)<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-203977375f17a88a6538f25b1808650f\"><a href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/\">Celecoxib<\/a><\/li>\n\n\n\n<li class=\"has-custom-her-st-r-du-color has-text-color has-link-color wp-elements-43749fc99202afbc25ca38325c9f22f4\"><a href=\"#nsaid\">NSAID\u2019er (scroll down)<\/a><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-fad7d0169f73487a5cb08247fb6344df\"><a href=\"https:\/\/jegharkraeft.dk\/en\/dipyridamole\/\">Heart and circulatory medications<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-110ab3157ece675d1aeb7921af0e506a\"><a href=\"https:\/\/jegharkraeft.dk\/en\/doxycycline\/\">Antibiotics and antiparasitic agents<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-a99575c8ffb4e827783ab6d56f16ed45\"><a href=\"https:\/\/jegharkraeft.dk\/en\/metformin\/\">Diabetes medication<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-6c31e64b006d888e2e94cb9770a3c32c\"><a href=\"https:\/\/jegharkraeft.dk\/en\/low-dose-naltrexone\/\">Agents affecting hormones and signaling substances<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-dd7ca0bc23a9ec3ca6e860ef8de7693a\"><a href=\"https:\/\/jegharkraeft.dk\/en\/disulfiram\/\">Other medications<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-66a0e4204f5201bcc8494f5822b38efe\"><a href=\"https:\/\/jegharkraeft.dk\/en\/the-coc-protocol\/\">COC Protocol<\/a><\/li>\n<\/ol>\n<\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-9504e56e950d068c15963cbdbf1fdaaf\"><a href=\"https:\/\/jegharkraeft.dk\/en\/no-medicine-plan-b\/\">No medication \u2013 Plan B<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-50bb8d7b4bb216418ba3c0d4a402648c\"><a href=\"https:\/\/jegharkraeft.dk\/en\/repurposed-drugs-and-chemotherapy\/\">Repurposed drugs and chemotherapy<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-af88e7f595afd58f141d2c174a141555\"><a href=\"https:\/\/jegharkraeft.dk\/en\/repurposed-drugs-and-radiotherapy\/\">Repurposed drugs and radiation therapy<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-7098df34ebce445cd1790d85e10991eb\"><a href=\"https:\/\/jegharkraeft.dk\/en\/flcccs-ranking\/\">FLCCC\u2019s ranking of repurposed drugs<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-4c827eb85783b3d07583409effc04d57\"><a href=\"https:\/\/jegharkraeft.dk\/en\/brain-metastases-and-bloodbrain-barrier\/\">Brain metastases and the blood-brain barrier<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-cf6cfac91ed1b7d193bc5d25a711b818\"><a href=\"https:\/\/jegharkraeft.dk\/en\/bombs-fire-extinguishers-and-timing\/\">Bombs, fire extinguishers, and timing<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bIbumetin1.jpg\" alt=\"Ibumetin i hvid og lilla papemballage med sort tekst, vist som eksempel p\u00e5 NSAID.\" class=\"wp-image-32943\" style=\"aspect-ratio:3\/2;object-fit:cover;width:550px\" srcset=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bIbumetin1.jpg 500w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bIbumetin1-300x300.jpg 300w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bIbumetin1-100x100.jpg 100w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bIbumetin1-150x150.jpg 150w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><\/figure>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull is-style-default has-global-padding is-layout-constrained wp-container-core-group-is-layout-b040ace0 wp-block-group-is-layout-constrained has-background\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--60);padding-right:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--60);padding-left:var(--wp--preset--spacing--20);background-image:url(&apos;https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bIbumetin1.jpg&apos;);background-position:44% 36%;background-size:cover;\">\n<div class=\"gb-element-8bddf08b\">\n<h1 class=\"wp-block-heading\" id=\"nsaid\"><span class=\"ez-toc-section\" id=\"NSAID_against_cancer\"><\/span>NSAID against cancer<span class=\"ez-toc-section-end\"><\/span><\/h1>\n\n\n\n<h4 class=\"wp-block-heading\">What is NSAID<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">NSAIDs (non-steroidal anti-inflammatory drugs) are a group of medications frequently used to relieve pain, fever, and inflammation. Examples of NSAIDs include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Ibuprofen <\/li>\n\n\n\n<li>Diclofenac <\/li>\n\n\n\n<li>Naproxen<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">They are effective in treating many common ailments. However, these substances have now also been shown to play a role in cancer treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Significance_of_NSAIDs_in_cancer_treatment\"><\/span>Significance of NSAIDs in cancer treatment<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">In recent years, researchers have discovered that NSAIDs can have a range of positive effects on cancer cells. These effects include:<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Inhibition of tumor growth<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">NSAIDs can also inhibit the production of prostaglandins, which are involved in cell growth and division. By reducing the production of prostaglandins, NSAIDs can potentially slow the growth of cancer cells.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Induction of cell death<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Some NSAIDs can directly induce programmed cell death (apoptosis) in cancer cells.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Reduction of Inflammation<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">One of the primary mechanisms behind the potential cancer-preventive effect of NSAIDs is their ability to inhibit inflammation. Chronic inflammation is linked to the development of many types of cancer.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Modulation of the immune system<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">By affecting the immune system, NSAIDs can help the body fight cancer cells more effectively.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"The_mechanism_behind_the_effect\"><\/span>The mechanism behind the effect<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">How exactly do NSAIDs work against cancer?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The short answer is that it is a complex interplay between various biological processes (this is elaborated further down in the text). One of the most important mechanisms is the inhibition of the enzyme cyclooxygenase (COX). COX plays a central role in the production of prostaglandins, which are molecules involved in inflammation and cell growth. By blocking COX, NSAIDs can reduce the production of prostaglandins and thereby inhibit the growth of cancer cells.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Clinical_studies_and_evidence\"><\/span>Clinical studies and evidence<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Several clinical studies have shown promising results regarding the use of NSAIDs in the prevention and treatment of various types of cancer, including: Several studies have suggested a link between regular use of NSAIDs and a lower risk of certain types of cancer, especially colorectal cancer.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Colorectal_cancer\"><\/span>Colorectal cancer<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">There is strong evidence that regular use of NSAIDs can reduce the risk of developing colorectal cancer. Several large epidemiological studies have shown a statistically significant correlation between regular use of NSAIDs and a reduced risk of this type of cancer.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Other_types_of_cancer\"><\/span>Other types of cancer<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Studies have also suggested a possible preventive effect of NSAIDs against other types of cancer, such as <a href=\"https:\/\/jegharkraeft.dk\/en\/spiseroerskraeft\/\">esophageal cancer<\/a>, <a href=\"https:\/\/jegharkraeft.dk\/en\/brystkraeft\/\">breast cancer<\/a>, <a href=\"https:\/\/jegharkraeft.dk\/en\/prostatakraeft\/\">prostate cancer<\/a>, and <a href=\"https:\/\/jegharkraeft.dk\/en\/lungekraeft\/\">lung cancer<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"NSAIDs_as_adjuvant_treatment\"><\/span>NSAIDs as adjuvant treatment<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">NSAIDs are often considered an adjuvant treatment, meaning they are used alongside other conventional cancer treatments, such as surgery, chemotherapy, and radiation therapy. Or they are used in combination with other repurposed drugs.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The combination of NSAIDs with other treatments can potentially increase the overall effect and improve patient outcomes.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Side_effects_of_NSAIDs\"><\/span>Side effects of NSAIDs<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">These may include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Maves\u00e5r <\/li>\n\n\n\n<li>Bl\u00f8dninger <\/li>\n\n\n\n<li>Nyreproblemer <\/li>\n\n\n\n<li>Hjerteproblemer<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">It is therefore crucial to speak with your doctor before starting treatment with NSAIDs, especially if you already have issues with any of the above.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Mechanisms_of_NSAIDs_in_cancer\"><\/span>Mechanisms of NSAIDs in cancer<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>(complicated)<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">As mentioned above, NSAIDs primarily inhibit the enzyme cyclooxygenase (COX). This enzyme plays a central role in the production of prostaglandins, which are signaling molecules involved in a wide range of biological processes, including inflammation, cell growth, and vasodilation. Here are some of the specific molecular mechanisms believed to be involved in the anticancer action of NSAIDs:<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Inhibition of tumor angiogenesis<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Prostaglandins play a crucial role in the formation of new blood vessels (angiogenesis), which is necessary for tumors to grow. By inhibiting the COX enzyme and thereby reducing prostaglandin production, NSAIDs can limit tumor growth by inhibiting angiogenesis.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Modulation of the cell cycle<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">NSAIDs can affect the cell cycle, which is the process by which cells grow and divide. By inducing cell cycle arrest, NSAIDs can prevent cancer cells from proliferating (growing or multiplying very quickly and extensively).<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Induction of apoptosis<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Some NSAIDs can induce programmed cell death (apoptosis) in cancer cells. This occurs by activating specific proteins involved in the apoptotic cascade.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Modulation of the tumor microenvironment<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">The tumor microenvironment is the local environment surrounding a tumor, and it plays an important role in tumor growth and progression. NSAIDs can affect the tumor microenvironment by reducing inflammation and increasing the immune response against tumor cells.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Interaction with other signaling pathways<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">In addition to COX inhibition, NSAIDs can also interact with other signaling pathways involved in cancer cell survival and proliferation, such as the NF-\u03baB and Akt pathways (both are signaling pathways in cells that play a central role in the development and spread of cancer).<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"COX-1_and_COX-2\"><\/span>COX-1 and COX-2<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">Two different isoforms<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">There are two main isoforms of the COX enzyme: COX-1 and COX-2. COX-1 is a constitutive enzyme expressed in most cells and is involved in normal physiological processes. COX-2 is an inducible enzyme (an enzyme whose production in a cell can be increased (induced) in response to a specific signal or substance) primarily expressed in inflammatory processes and in cancer cells.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Side_effects_and_challenges\"><\/span>Side effects and challenges<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Most conventional NSAIDs inhibit both COX-1 and COX-2, which can lead to side effects such as gastric ulcers and bleeding. The development of selective COX-2 inhibitors (such as celecoxib) was therefore a major advancement, as these drugs were intended to be gentler on the gastrointestinal tract. However, later studies have shown that selective COX-2 inhibitors can also have serious side effects, including an increased risk of heart attack and stroke.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"A_complex_picture\"><\/span>A complex picture<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Although significant knowledge has been gained regarding the molecular mechanisms behind the anticancer effect of NSAIDs, many unanswered questions remain. Cancer is a complex disease, and the effect of NSAIDs can vary depending on the tumor type, stage, and the individual patient&#8217;s genetic makeup.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Conclusion\"><\/span>Conclusion<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">NSAIDs represent an exciting area of research within cancer treatment. Although there is still much we do not know, it is clear that these common painkillers have significant potential to improve the treatment of cancer patients. By combining NSAIDs with other therapies, we may one day achieve more effective and gentler treatment for cancer.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you are in doubt about interactions, they can be checked here: <\/p>\n\n\n\n<p class=\"has-custom-bl-links-color has-text-color has-link-color wp-elements-44e9f8537547201e0b860469b007bb4f wp-block-paragraph\"><a href=\"https:\/\/www.drugs.com\/?fbclid=IwZXh0bgNhZW0CMTAAAR2Un76TmB0Yk4p7gHQ4TUFL7cCg_ob3aVB1DcZjT48o-YwFap8riMvnNiQ_aem__ZDuOwAdzVO0yZi5iJKihQ\" target=\"_blank\" rel=\"noreferrer noopener\">Drugs.com<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">See also <a href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/\">Celecoxib<\/a><a href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/\"><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">See also <a href=\"https:\/\/jegharkraeft.dk\/en\/repurposed-drugs\/\">Repurposed Drugs<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">See also <a href=\"https:\/\/jegharkraeft.dk\/en\/no-medicine-plan-b-2\/\">No medicine &#8211; Plan B<\/a><a href=\"https:\/\/jegharkraeft.dk\/en\/repurposed-drugs\/\"><\/a><\/p>\n\n\n\n<p class=\"has-custom-menu-links-color has-text-color has-link-color wp-elements-c20aaf8639fe4bc173676d2851829423 wp-block-paragraph\"><a href=\"#menu\">(til menu)<\/a><a href=\"https:\/\/jegharkraeft.dk\/en\/repurposed-drugs\/\"><\/a><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Links<\/h4>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-90c47cff7e3de9a63bad5c7980364c20 wp-block-paragraph\"><a href=\"https:\/\/www.interaktionsdatabasen.dk\/\" target=\"_blank\" rel=\"noopener\">Interactions<\/a> (search for preparations) (Interaktionsdatabasen, Danish Medicines Agency) (Danish Language)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-54e6f0f00677118a53d27c9d28e14e3f wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35163356\/\" target=\"_blank\" rel=\"noreferrer noopener\">NSAIDs and Cancer Resolution: New Paradigms beyond Cyclooxygenase<\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35163356\/\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a>(PubMed)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-f393359288c485e3deb91be31cd48a6e wp-block-paragraph\"><a href=\"https:\/\/www.dr.dk\/nyheder\/regionale\/oestjylland\/smertestillende-piller-kan-forebygge-kraeft\" target=\"_blank\" rel=\"noopener\">Painkillers can prevent cancer<\/a> (DR-Nyheder) (Danish Language)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-73a9ff2807798b03e056a9248cdef92d wp-block-paragraph\"><a href=\"https:\/\/ugeskriftet.dk\/videnskab\/nonsteroide-antiinflammatoriske-farmaka-og-forebyggelse-af-kolorektalcancer-og-andre\" target=\"_blank\" rel=\"noopener\">Non-steroidal anti-inflammatory drugs and prevention of colorectal cancer and other forms of cancer <\/a>(Ugeskrift for L\u00e6ger) (Danish Language)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-82378921773e14d9f0f08237069badef wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11929340\/\" target=\"_blank\" rel=\"noreferrer noopener\">NSAIDs and gastrointestinal cancer prevention<\/a> (PubMed)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-e99e0f473f208d9b4fc11c79ade75232 wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32283655\/\" target=\"_blank\" rel=\"noreferrer noopener\">Anti-Inflammatory Drugs as Anticancer Agents<\/a> (PubMed)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-11c095f812af7db82901e46112faaa91 wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18194278\/\" target=\"_blank\" rel=\"noreferrer noopener\">NSAIDs and breast cancer: a possible prevention and treatment strategy<\/a> (PubMed)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-3328faa118591f0d3f609d3fc18d18f7 wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20844293\/\" target=\"_blank\" rel=\"noreferrer noopener\">Effect of aspirin and NSAIDs on risk and survival from colorectal cancer<\/a> (PubMed)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-61548dc8111c5e24951e0c1767a62653 wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19213572\/\" target=\"_blank\" rel=\"noreferrer noopener\">Aspirin and NSAIDs for the prevention of colorectal cancer<\/a> (PubMed)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Page created:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">July 1, 2024, Last revised October 28, 2024<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-menu-links-color\">\u2764<\/mark><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>What you read on Jeg har Kr\u00e6ft is not a recommendation. Seek competent guidance.<\/strong><\/p>\n<\/div>\n<\/div>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Indhold<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/#Treatments\" >Treatments<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/#Complementary_and_Alternative_Treatments\" >Complementary and Alternative Treatments<\/a><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/#NSAID_against_cancer\" >NSAID against cancer<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/#Significance_of_NSAIDs_in_cancer_treatment\" >Significance of NSAIDs in cancer treatment<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/#The_mechanism_behind_the_effect\" >The mechanism behind the effect<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/#Clinical_studies_and_evidence\" >Clinical studies and evidence<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/#Colorectal_cancer\" >Colorectal cancer<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/#Other_types_of_cancer\" >Other types of cancer<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/#NSAIDs_as_adjuvant_treatment\" >NSAIDs as adjuvant treatment<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/#Side_effects_of_NSAIDs\" >Side effects of NSAIDs<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/#Mechanisms_of_NSAIDs_in_cancer\" >Mechanisms of NSAIDs in cancer<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/#COX-1_and_COX-2\" >COX-1 and COX-2<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/#Side_effects_and_challenges\" >Side effects and challenges<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/#A_complex_picture\" >A complex picture<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/#Conclusion\" >Conclusion<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Treatments Complementary and Alternative Treatments NSAID against cancer What is NSAID NSAIDs (non-steroidal anti-inflammatory drugs) are a group of medications frequently used to relieve pain, fever, and inflammation. Examples of NSAIDs include: They are effective in treating many common ailments. However, these substances have now also been shown to play a role in cancer treatment. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":32943,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[393,375,374,394],"tags":[],"class_list":["post-32944","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-repurposed-drugs","category-alternative-treatments","category-treatments","category-cell-cycle-and-angiogenesis-inhibitors"],"modified_by":"Hanne Kj\u00e6r Uhlig","wpml_current_locale":"en_US","wpml_translations":[],"_links":{"self":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts\/32944","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/comments?post=32944"}],"version-history":[{"count":1,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts\/32944\/revisions"}],"predecessor-version":[{"id":33829,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts\/32944\/revisions\/33829"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/media\/32943"}],"wp:attachment":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/media?parent=32944"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/categories?post=32944"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/tags?post=32944"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}