{"id":32938,"date":"2025-03-21T19:25:39","date_gmt":"2025-03-21T18:25:39","guid":{"rendered":"https:\/\/jegharkraeft.dk\/?p=32938"},"modified":"2026-04-11T18:54:07","modified_gmt":"2026-04-11T17:54:07","slug":"celecoxib","status":"publish","type":"post","link":"https:\/\/jegharkraeft.dk\/en\/celecoxib\/","title":{"rendered":"Celecoxib"},"content":{"rendered":"\n<div class=\"wp-block-group alignfull is-style-section-5 has-contrast-color has-base-background-color has-text-color has-background has-link-color wp-elements-8184c3d51dd9409d0ef6d28842b8f742 has-global-padding is-layout-constrained wp-block-group-is-layout-constrained is-style-section-5--2\" id=\"menu\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--50);padding-bottom:var(--wp--preset--spacing--50)\">\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-ca2dd60b wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-85c9ab605a9af581478ba1bfba8fd611\"><span class=\"ez-toc-section\" id=\"Treatments\"><\/span><a href=\"https:\/\/jegharkraeft.dk\/en\/cancer-treatments-overview\/\">Treatments<\/a><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-52532d4beacf4a32227a79286a8276fc\"><span class=\"ez-toc-section\" id=\"Complementary_and_Alternative_Treatments\"><\/span><a href=\"https:\/\/jegharkraeft.dk\/en\/alternative-cancer-treatments-overview\/\">Complementary and Alternative Treatments<\/a><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<div class=\"wp-block-group has-custom-interne-links-color has-text-color has-link-color wp-elements-6783cb2f088b0c0e26a703bef5837796 has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<ol class=\"wp-block-list\">\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-03aa8b06ac54b12d6e2a75c1d07f7166\"><a href=\"https:\/\/jegharkraeft.dk\/akupunktur\/\">Physical treatments<\/a>\n<ul class=\"wp-block-list\">\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-897d2bb32589f598487001098a8465aa\"><a href=\"https:\/\/jegharkraeft.dk\/en\/repurposed-drugs\/\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-hvid-tekst-color\">Repurposed Drugs &#8211; General<\/mark><\/a>\n<ol class=\"wp-block-list\">\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-9a415e3b512bc2df9c6173c571c9c7cf\"><a href=\"https:\/\/jegharkraeft.dk\/en\/aspirin\/\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-hvid-tekst-color\">Painkillers and anti-inflammatory drugs<\/mark><\/a>\n<ul class=\"wp-block-list\">\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-a8a06d6d6717f6b088349d66369c07d1\"><a href=\"https:\/\/jegharkraeft.dk\/en\/aspirin\/\">Aspirin (low-dose acetylsalicylic)<\/a><\/li>\n\n\n\n<li class=\"has-custom-her-st-r-du-color has-text-color has-link-color wp-elements-bffa7ed0c75c52e716e0e0bb20c64fa9\"><a href=\"#celecoxib\">Celecoxib (scroll down)<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/jegharkraeft.dk\/en\/nsaid-against-cancer\/\">NSAID\u2019er<\/a><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-fad7d0169f73487a5cb08247fb6344df\"><a href=\"https:\/\/jegharkraeft.dk\/en\/dipyridamole\/\">Heart and circulatory medications<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-110ab3157ece675d1aeb7921af0e506a\"><a href=\"https:\/\/jegharkraeft.dk\/en\/doxycycline\/\">Antibiotics and antiparasitic agents<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-a99575c8ffb4e827783ab6d56f16ed45\"><a href=\"https:\/\/jegharkraeft.dk\/en\/metformin\/\">Diabetes medication<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-6c31e64b006d888e2e94cb9770a3c32c\"><a href=\"https:\/\/jegharkraeft.dk\/en\/low-dose-naltrexone\/\">Agents affecting hormones and signaling substances<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-dd7ca0bc23a9ec3ca6e860ef8de7693a\"><a href=\"https:\/\/jegharkraeft.dk\/en\/disulfiram\/\">Other medications<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-66a0e4204f5201bcc8494f5822b38efe\"><a href=\"https:\/\/jegharkraeft.dk\/en\/the-coc-protocol\/\">COC Protocol<\/a><\/li>\n<\/ol>\n<\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-9504e56e950d068c15963cbdbf1fdaaf\"><a href=\"https:\/\/jegharkraeft.dk\/en\/no-medicine-plan-b\/\">No medication \u2013 Plan B<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-50bb8d7b4bb216418ba3c0d4a402648c\"><a href=\"https:\/\/jegharkraeft.dk\/en\/repurposed-drugs-and-chemotherapy\/\">Repurposed drugs and chemotherapy<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-af88e7f595afd58f141d2c174a141555\"><a href=\"https:\/\/jegharkraeft.dk\/en\/repurposed-drugs-and-radiotherapy\/\">Repurposed drugs and radiation therapy<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-7098df34ebce445cd1790d85e10991eb\"><a href=\"https:\/\/jegharkraeft.dk\/en\/flcccs-ranking\/\">FLCCC\u2019s ranking of repurposed drugs<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-4c827eb85783b3d07583409effc04d57\"><a href=\"https:\/\/jegharkraeft.dk\/en\/brain-metastases-and-bloodbrain-barrier\/\">Brain metastases and the blood-brain barrier<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-cf6cfac91ed1b7d193bc5d25a711b818\"><a href=\"https:\/\/jegharkraeft.dk\/en\/bombs-fire-extinguishers-and-timing\/\">Bombs, fire extinguishers, and timing<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"1000\" src=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bCelecoxib.jpg\" alt=\"Celecoxib i papemballage. Hvid med sort skrift og bl\u00e5 m\u00e6rkning. 200 mg. capsler.\" class=\"wp-image-32937\" style=\"aspect-ratio:3\/2;object-fit:cover;width:550px\" srcset=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bCelecoxib.jpg 1000w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bCelecoxib-300x300.jpg 300w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bCelecoxib-100x100.jpg 100w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bCelecoxib-600x600.jpg 600w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bCelecoxib-150x150.jpg 150w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bCelecoxib-768x768.jpg 768w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull is-style-default has-global-padding is-layout-constrained wp-container-core-group-is-layout-b040ace0 wp-block-group-is-layout-constrained has-background\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--60);padding-right:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--60);padding-left:var(--wp--preset--spacing--20);background-image:url(&apos;https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bCelecoxib.jpg&apos;);background-position:44% 36%;background-size:cover;\">\n<div class=\"gb-element-8bddf08b\">\n<h1 class=\"wp-block-heading\" id=\"celecoxib\"><span class=\"ez-toc-section\" id=\"Celecoxib_and_cancer\"><\/span>Celecoxib and cancer<span class=\"ez-toc-section-end\"><\/span><\/h1>\n\n\n\n<h4 class=\"wp-block-heading\">What is celecoxib?<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) primarily used to treat pain and inflammation. It belongs to a class of drugs called COX-2 inhibitors, which specifically target the cyclooxygenase-2 (COX-2) enzyme involved in inflammation and pain. Celecoxib is often used to treat conditions such as osteoarthritis, rheumatoid arthritis, and acute pain. One advantage is that it generally has a lower risk of gastrointestinal side effects compared to traditional NSAIDs, though it can still pose risks such as cardiovascular problems.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Celecoxib has in recent years attracted significant attention in cancer research. This interest stems from the drug\u2019s potential to inhibit tumor cell growth and reduce cancer spread.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Why_celecoxib\"><\/span>Why celecoxib<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Celecoxib is a selective COX-2 inhibitor. COX-2 is an enzyme that plays a central role in the production of prostaglandins, substances that promote inflammation and pain. However, COX-2 is also involved in several other processes, including cell growth, blood vessel development (angiogenesis), and tumorigenesis (the transformation of normal cells into cancer cells).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Effect_of_celecoxib\"><\/span>Effect of celecoxib<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The primary mechanisms by which celecoxib is believed to act as an anticancer agent include:<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Inhibition of inflammation<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Cancer cells often create an inflammatory environment that can promote tumor growth and spread. By inhibiting COX-2, a key enzyme in the inflammatory process, celecoxib may potentially counteract this.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Effect on angiogenesis<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Celecoxib can influence the formation of new blood vessels (angiogenesis), which is crucial for tumor growth. By inhibiting angiogenesis, celecoxib may potentially slow tumor development.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Induction of apoptosis<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Apoptosis is programmed cell death. Celecoxib can stimulate apoptosis in cancer cells, leading to their demise.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Modulation of the cell cycle<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Celecoxib can affect the cell cycle, which may prevent cancer cells from dividing and growing.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Enhancing other cancer treatments<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">There is evidence that celecoxib may increase sensitivity to other cancer treatments, such as chemotherapy and radiation therapy.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Biopsi\"><\/span>Biopsi<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">One of the links below leads to an article about the prophylactic use of celecoxib in connection with biopsy collection, where it is injected into the cavity. This procedure is performed to reduce the risk of seeding (which, if left unchecked by the immune system, can lead to metastases).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It is possible to imagine that it might also be beneficial to take celecoxib in pill form a few hours after a biopsy is taken (and then daily for a week, or as your healthcare provider recommends). (For example, ibuprofen or similar, which is available over the counter.) However, this is my own theory, for which I have no evidence.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Of course, you should only consider taking NSAIDs if you tolerate these medications and have no conditions that make it contraindicated. Additionally, be aware that it may increase the risk of bleeding, so you should avoid taking it before a biopsy. Do not take NSAIDs on an empty stomach.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It has always concerned me to undergo a biopsy. I like the idea of being able to do something to minimize the risk of seeding.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For more details on the effect, see the bottom of the page\u2014separate section.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For the Nerds <a href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#celecoxib1tekst\"><strong>(scroll down)<\/strong><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Cancer_types_that_are_particularly_sensitive\"><\/span>Cancer types that are particularly sensitive<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Research has particularly focused on celecoxib\u2019s potential in relation to:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/jegharkraeft.dk\/tarmkraeft\/\"><strong>Colorectal cancer<\/strong><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Promising results suggest that celecoxib may reduce the risk of developing colorectal cancer in people with a hereditary predisposition.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/jegharkraeft.dk\/prostatakraeft\/\"><strong>Prostate cancer<\/strong><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Some studies have shown a possible preventive effect of celecoxib against prostate cancer.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Other cancer types<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">There are also ongoing studies regarding other cancer types, such as <a href=\"https:\/\/jegharkraeft.dk\/lungekraeft\/\">lung cancer<\/a> and <a href=\"https:\/\/jegharkraeft.dk\/brystkraeft\/\">breast cancer<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Side_effects\"><\/span>Side effects<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Like many other medications, celecoxib can cause side effects. While not everyone experiences them, it is important to be aware of the potential risks.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Common side effects:<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Gastrointestinal issues (most common): This may include stomach pain, heartburn, diarrhea, constipation, nausea, and vomiting.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Headache<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Dizziness: Some people may feel dizzy or drowsy.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Skin: Rash, itching, or other skin reactions may occur.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"More_serious_side_effects_requiring_immediate_medical_attention\"><\/span>More serious side effects requiring immediate medical attention<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Heart attack and stroke<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Although the risk is small, long-term use of celecoxib may increase the risk of heart attack and stroke, especially in people with cardiovascular disease or risk factors.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Bleeding<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Celecoxib can increase the risk of bleeding, both in the gastrointestinal tract and elsewhere in the body.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Kidney problems<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>In rare cases, celecoxib may cause kidney problems.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Severe allergic reactions<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>These are rare but can be life-threatening. Symptoms may include rash, swelling of the face, lips, tongue, or throat, and difficulty breathing.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Who_should_be_cautious_with_celecoxib\"><\/span>Who should be cautious with celecoxib<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>People with cardiovascular disease<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Due to the risk of heart attack and stroke, people with heart problems or risk factors for these conditions should be cautious.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>People with stomach ulcers or bleeding<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Celecoxib can irritate the stomach lining and increase the risk of bleeding.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>People with kidney or liver problems<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Impaired kidney or liver function can affect how the body breaks down celecoxib. See also: Liver and kidney values.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Pregnant and breastfeeding women<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>There is limited knowledge about the safety of using celecoxib during pregnancy and breastfeeding.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Challenges\"><\/span>Challenges<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Although there are promising results, there are still many unanswered questions, and the research is complex. Some of the challenges include:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Sideeffects<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Like other NSAIDs, celecoxib can cause serious side effects, including an increased risk of heart attack and stroke.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Limited effectiveness as monotherapy<\/strong><br>Celecoxib appears to be most effective when combined with other cancer treatments.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Resistance<\/strong><br>Cancer cells can develop resistance to celecoxib, which may limit the drug\u2019s effectiveness over time.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Note\"><\/span>Note<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Individual reactions<\/strong><br>Side effects vary from person to person. Some experience none or only mild side effects, while others may be more sensitive.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Concurrent medication<\/strong><br>Celecoxib can interact with other medications, so it is important to inform your doctor about all the medications you are taking.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Dosage and duration<\/strong><br>It is important to follow your doctor\u2019s instructions carefully regarding dosage and duration of treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Conclusion\"><\/span>Conclusion<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Celecoxib represents a promising example of how an existing drug can be repurposed to fight cancer. While there are still challenges to overcome, there is no doubt that this drug has great potential to revolutionize cancer treatment.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Future perspectives<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Research into celecoxib as an anticancer agent is still ongoing. There is great potential for combining celecoxib with other drugs and therapies to achieve more effective cancer treatment. In addition, new formulations and routes of administration are being investigated to minimize side effects and increase the drug\u2019s effectiveness.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you are unsure about interactions, you can check here:<\/p>\n\n\n\n<p class=\"has-custom-bl-links-color has-text-color has-link-color wp-elements-e5573d2edb548cbf9a683e50be6153ba wp-block-paragraph\"><a rel=\"noreferrer noopener\" href=\"https:\/\/www.drugs.com\/?fbclid=IwZXh0bgNhZW0CMTAAAR2Un76TmB0Yk4p7gHQ4TUFL7cCg_ob3aVB1DcZjT48o-YwFap8riMvnNiQ_aem__ZDuOwAdzVO0yZi5iJKihQ\" target=\"_blank\"><strong>Drugs.com<\/strong><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">See also <a href=\"https:\/\/jegharkraeft.dk\/en\/repurposed-drugs\/\"><strong>Repurposed Drugs<\/strong><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Continued\u2026<\/strong><\/p>\n\n\n\n<p class=\"has-custom-menu-links-color has-text-color has-link-color wp-elements-ef7d07e4a2f3fd4865240f3b1020f6b6 wp-block-paragraph\"><a href=\"#menu\">(to menu)<\/a><a href=\"https:\/\/jegharkraeft.dk\/en\/repurposed-drugs\/\"><\/a><\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Links<\/strong><\/h4>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-21aab55095bf6390361e8c759a7afced wp-block-paragraph\"><a href=\"https:\/\/www.interaktionsdatabasen.dk\/\" target=\"_blank\" rel=\"noopener\">Interactions (search for medications)<\/a> (Interaktionsdatabasen, Danish Medicines Agency) (Danish Language)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-ac9c7e2e36aa36ebbff4e0cd23f7d7c1 wp-block-paragraph\"><a href=\"https:\/\/www.rigshospitalet.dk\/undersoegelse-og-behandling\/find-undersoegelse-og-behandling\/Sider\/Celecoxib---forebyggende-behandling-29611.aspx\" target=\"_blank\" rel=\"noopener\">Celecoxib \u2013 preventive treatment<\/a> (Rigshospitalet) (Danish Language)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-d2cab6ddfea6652f02b56ee5d92f67df wp-block-paragraph\"><a href=\"https:\/\/min.medicin.dk\/Medicin\/Praeparater\/7598\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Celecoxib &#8220;Krka&#8221;<\/strong><\/a> (Medicin.dk) (Danish Language)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-9a051b6be330e5d9e20a7db1cbef5e30 wp-block-paragraph\"><a href=\"https:\/\/dagensmedicin.dk\/smertestillende-midler-kan-hamme-brystkraft\/\" target=\"_blank\" rel=\"noopener\">Painkillers may inhibit breast cancer<\/a> (Dagens Medicin) (Danish Language)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-f77b650344ca061d34cfef7f493522af wp-block-paragraph\"><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38990306\/\" target=\"_blank\"><strong>Celecoxib inhibits NLRP1 inflammasome pathway in MDA-MB-231 Cells<\/strong><\/a> (PubMed)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-d561c754fcdec2ba2a8011211417e330 wp-block-paragraph\"><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38969944\/\" target=\"_blank\"><strong>Sustained delivery of celecoxib from nanoparticles embedded in hydrogel injected into the biopsy cavity to prevent biopsy-induced breast cancer metastasis<\/strong><\/a> (PubMed)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-77719a75e9d31aaed0daeaee2bb79063 wp-block-paragraph\"><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38996202\/\" target=\"_blank\"><strong>Differential inflammatory conditioning of the bone marrow by acute myeloid leukemia and its impact on progression<\/strong><\/a> (PubMed)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-d20bc281b9cf20e10d53cb1b65d4d31a wp-block-paragraph\"><strong>Page created:<\/strong><\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-0b396147066e7a77df39c359011cd7be wp-block-paragraph\">October 27, 2024<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-menu-links-color\">\u2764<\/mark><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>What you read on I Have Cancer is not a recommendation. Seek competent guidance.<\/em><\/strong><\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull is-style-default has-global-padding is-layout-constrained wp-container-core-group-is-layout-b040ace0 wp-block-group-is-layout-constrained has-background\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--60);padding-right:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--60);padding-left:var(--wp--preset--spacing--20);background-image:url(&apos;https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/02\/bCelecoxib.jpg&apos;);background-position:44% 36%;background-size:cover;\">\n<div class=\"gb-element-906497af\">\n<h2 class=\"wp-block-heading\" id=\"celecoxib-noerdede\"><span class=\"ez-toc-section\" id=\"Celecoxib_and_cancer_%E2%80%93_The_nerdy_part\"><\/span>Celecoxib and cancer &#8211;<br>The nerdy part<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Molecular action of the anticancer effect<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">The anticancer effect of Celecoxib is complex and involves several molecular mechanisms.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Central_mechanisms\"><\/span>Central mechanisms<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Inhibition of cyclooxygenase-2 (COX-2):<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">COX-2 is an enzyme that plays a central role in the production of prostaglandins, which are involved in inflammation, cell proliferation, and angiogenesis. By inhibiting COX-2, Celecoxib reduces the production of prostaglandins, which can lead to:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Reduced inflammation:<\/strong> Cancer cells often thrive in an inflammatory environment. By reducing inflammation, Celecoxib can inhibit tumor growth.<\/li>\n\n\n\n<li><strong>Inhibited angiogenesis:<\/strong> Prostaglandins play an important role in the formation of new blood vessels (angiogenesis), which is necessary for tumor growth.<\/li>\n\n\n\n<li><strong>Modulation of the cell cycle:<\/strong> Prostaglandins can affect the cell cycle and promote cell proliferation. By inhibiting COX-2, Celecoxib can disrupt this process.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">Induction of apoptosis<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Apoptosis is programmed cell death. Celecoxib can induce apoptosis in cancer cells by affecting various signaling pathways, including the caspase cascade. Caspases are a family of proteases (enzymes that break down proteins). These caspases initiate a cascade within the cell that destroys proteins and kills the cell, thereby initiating apoptosis and mitochondrial function.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Modulation_of_cell_adhesion_and_migration\"><\/span>Modulation of cell adhesion and migration<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Cancer cells often have decreased cell adhesion (when cells bind to each other or to a surface) and increased migration capacity (the cell&#8217;s ability to move from the original site where it arose to other parts of the body), which facilitates invasion and metastasis. Celecoxib can affect these processes by regulating the expression of adhesion molecules and proteases. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Or put another way:<\/strong> <\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Inside our bodies, cells have small &#8220;handles&#8221; called adhesion molecules, which they use to hold onto each other. Cancer cells can have too many of these &#8220;handles,&#8221; making it easier for them to spread. Celecoxib can affect the production of these &#8220;handles&#8221; and certain other substances that help cancer cells penetrate tissue. In this way, Celecoxib can make it harder for cancer cells to move around the body.<\/em><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Interaction with other signaling pathways<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Celecoxib can interact with other signaling pathways, such as NF-\u03baB, MAPK, and PI3K\/Akt, which are involved in cell survival, proliferation, and invasion. By modulating (affecting) these pathways in cancer cells, Celecoxib can inhibit tumor growth. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Or put another way: <\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Cancer cells have a special system that tells them how to behave. Celecoxib can go in and disrupt this system so that the cancer cells can no longer follow their &#8220;orders.&#8221; In this way, Celecoxib can help stop the cancer from growing.<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Molecular_targets\"><\/span>Molecular targets<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>NF-\u03baB:<\/strong> A key transcription factor that regulates the expression of genes involved in inflammation and cell survival. Celecoxib can inhibit NF-\u03baB activation.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>The MAPK pathway:<\/strong> A signaling pathway involved in cell proliferation, differentiation, and apoptosis. Celecoxib can inhibit the activation of the MAPK pathway.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>The PI3K\/Akt pathway:<\/strong> A central signaling pathway involved in cell survival, proliferation, and angiogenesis. Celecoxib can inhibit this pathway.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Summary\"><\/span>Summary<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The anticancer effect of Celecoxib is multifactorial and involves a complex interaction with several molecular targets and signaling pathways. By inhibiting inflammation and angiogenesis, inducing apoptosis, and modulating the cell cycle and adhesion, Celecoxib can effectively inhibit tumor growth and spread.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Or put another way:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Celecoxib: This drug can disrupt these important processes in cancer cells so they can no longer grow and spread.<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>In short: Celecoxib is like a spy that enters the cancer cells and sabotages their operations. In this way, it can help stop the cancer from growing.<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you are in doubt about interactions, they can be checked here:<\/p>\n\n\n\n<p class=\"has-custom-bl-links-color has-text-color has-link-color wp-elements-e5573d2edb548cbf9a683e50be6153ba wp-block-paragraph\"><a rel=\"noreferrer noopener\" href=\"https:\/\/www.drugs.com\/?fbclid=IwZXh0bgNhZW0CMTAAAR2Un76TmB0Yk4p7gHQ4TUFL7cCg_ob3aVB1DcZjT48o-YwFap8riMvnNiQ_aem__ZDuOwAdzVO0yZi5iJKihQ\" target=\"_blank\"><strong>Drugs.com<\/strong><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">See also <a href=\"https:\/\/jegharkraeft.dk\/en\/repurposed-drugs\/\"><strong>Repurposed Drugs<\/strong><\/a><\/p>\n\n\n\n<p class=\"has-custom-menu-links-color has-text-color has-link-color wp-elements-ef7d07e4a2f3fd4865240f3b1020f6b6 wp-block-paragraph\"><a href=\"#menu\">(to menu)<\/a><a href=\"https:\/\/jegharkraeft.dk\/en\/repurposed-drugs\/\"><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Page created:<\/strong> October 27, 2024<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-menu-links-color\">\u2764<\/mark><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>What you read on Jeg har Kr\u00e6ft is not a recommendation. Seek competent guidance.<\/em><\/strong><\/p>\n<\/div>\n<\/div>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Indhold<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Treatments\" >Treatments<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Complementary_and_Alternative_Treatments\" >Complementary and Alternative Treatments<\/a><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Celecoxib_and_cancer\" >Celecoxib and cancer<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Why_celecoxib\" >Why celecoxib<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Effect_of_celecoxib\" >Effect of celecoxib<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Biopsi\" >Biopsi<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Cancer_types_that_are_particularly_sensitive\" >Cancer types that are particularly sensitive<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Side_effects\" >Side effects<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#More_serious_side_effects_requiring_immediate_medical_attention\" >More serious side effects requiring immediate medical attention<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Who_should_be_cautious_with_celecoxib\" >Who should be cautious with celecoxib<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Challenges\" >Challenges<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Note\" >Note<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Conclusion\" >Conclusion<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Celecoxib_and_cancer_%E2%80%93_The_nerdy_part\" >Celecoxib and cancer &#8211; The nerdy part<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Central_mechanisms\" >Central mechanisms<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Modulation_of_cell_adhesion_and_migration\" >Modulation of cell adhesion and migration<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Molecular_targets\" >Molecular targets<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/jegharkraeft.dk\/en\/celecoxib\/#Summary\" >Summary<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Treatments Complementary and Alternative Treatments Celecoxib and cancer What is celecoxib? Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) primarily used to treat pain and inflammation. It belongs to a class of drugs called COX-2 inhibitors, which specifically target the cyclooxygenase-2 (COX-2) enzyme involved in inflammation and pain. Celecoxib is often used to treat conditions such [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":32937,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[393,375,374,394],"tags":[],"class_list":["post-32938","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-repurposed-drugs","category-alternative-treatments","category-treatments","category-cell-cycle-and-angiogenesis-inhibitors"],"modified_by":"Hanne Kj\u00e6r Uhlig","wpml_current_locale":"en_US","wpml_translations":[],"_links":{"self":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts\/32938","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/comments?post=32938"}],"version-history":[{"count":1,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts\/32938\/revisions"}],"predecessor-version":[{"id":33825,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts\/32938\/revisions\/33825"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/media\/32937"}],"wp:attachment":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/media?parent=32938"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/categories?post=32938"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/tags?post=32938"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}