{"id":31294,"date":"2025-04-18T11:00:00","date_gmt":"2025-04-18T10:00:00","guid":{"rendered":"https:\/\/jegharkraeft.dk\/?p=31294"},"modified":"2026-04-28T20:39:13","modified_gmt":"2026-04-28T19:39:13","slug":"agaricus-blazei-murill","status":"publish","type":"post","link":"https:\/\/jegharkraeft.dk\/en\/agaricus-blazei-murill\/","title":{"rendered":"1. Agaricus blazei Murill (ABM), medicinal mushroom and cancer. Medicinal mushrooms"},"content":{"rendered":"\n<div class=\"wp-block-group alignfull is-style-section-5 has-contrast-color has-base-background-color has-text-color has-background has-link-color wp-elements-6cb340010065f7bb2b66d076517d3cdc has-global-padding is-layout-constrained wp-block-group-is-layout-constrained is-style-section-5--2\" id=\"menu\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--50);padding-bottom:var(--wp--preset--spacing--50)\">\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-ca2dd60b wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-f7c7130b7f4e4bc7c42d38d3d74a57a6\"><span class=\"ez-toc-section\" id=\"Dietary_Supplements_Grouped_by_Effect\"><\/span><a href=\"https:\/\/jegharkraeft.dk\/en\/kosttilskud-grupperet\/\">Dietary Supplements Grouped by Effect<\/a><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Dietary_Supplements_Alphabetical\"><\/span><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-her-st-r-du-color\"><a href=\"https:\/\/jegharkraeft.dk\/en\/supplements-alphabetically\/\">Dietary Supplements Alphabetical<\/a><\/mark><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h4 class=\"wp-block-heading has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-1fbbe67406ce3c177ab61028dcf865f5\"><a href=\"https:\/\/jegharkraeft.dk\/en\/acai-berries-and-cancer\/\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-hvid-tekst-color\">A<\/mark>,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/baicalin\/\">B,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/cats-claw-tomentosa\/\">C,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/danshen\/\">D,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/echinacea\/\">E+F,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/garcinia-cambogia\/\">G,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/hemp-seeds\/\">H,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/indol-3-carbinol\/\">I+J+K,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/lions-mane\/\">L,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/maitake\/\">M,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/n-acetyl-cysteine\/\">N,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/omega-3\/\">O,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/peppermint\/pebermynte\/\">P<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-interne-links-color\">,<\/mark><\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/quercetin\/\">Q,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/reishi\/\">R,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/selenium\/\">S,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/thc-cannabis\/\">T,<\/a><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-sort-tekst-color\">.<\/mark> <a href=\"https:\/\/jegharkraeft.dk\/en\/vitamin-b\/\">U+V+Z<\/a><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-7328fd361576b7b409ea8903f99fbabf\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-her-st-r-du-color\"><a href=\"https:\/\/jegharkraeft.dk\/en\/acai-berries-and-cancer\/\">Acai-berry<\/a><\/mark><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-1bf3b438e807bc1e659fe8e5d9d6eeff\"><a href=\"https:\/\/jegharkraeft.dk\/en\/carnitine\/\">Acetyl L-carnitine<\/a><\/li>\n\n\n\n<li class=\"has-custom-her-st-r-du-color has-text-color has-link-color wp-elements-d491ea6a86dc317c16408930d4d1e1f2\"><a href=\"#agaricus-blazei-murill\">Agaricus blazei Murill (ABM) (medicinal mushroom) (scroll down)<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-74b569af92080fb5ec0aebda82f54a9e\"><a href=\"https:\/\/jegharkraeft.dk\/en\/ahcc\/\">AHCC<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-20c0f2c3adb68f6c91266b58c7df6b96\"><a href=\"https:\/\/jegharkraeft.dk\/en\/akkermansia\/\">Akkermansia<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-fe8ff40dfb210c716dced8e257237f24\"><a href=\"https:\/\/jegharkraeft.dk\/en\/activated-charcoal\/\">Activated charcoal<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-b2258379f707d87b64d062906b0a5c76\"><a href=\"https:\/\/jegharkraeft.dk\/en\/alpha-lipoic-acid\/\">Alpha-lipoic acid<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-b652abba3ce386219ac8e18a818493ac\"><a href=\"https:\/\/jegharkraeft.dk\/en\/aloe-vera\/\">Aloe Vera<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-c9b61b896f9c7a2e388f12e525268834\"><a href=\"https:\/\/jegharkraeft.dk\/en\/amygdalin\/\">Amygdalin<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-6f83b438a61e3d2e59a91eab277d30d5\"><a href=\"https:\/\/jegharkraeft.dk\/en\/andrographis\/\">Andrographis Paniculata<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-4b182c9f6c03d5e8a84da30591d5c40e\"><a href=\"https:\/\/jegharkraeft.dk\/en\/apigenin\/\">Apigenin<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-6210823f96250dbb40259688088a6434\"><a href=\"https:\/\/jegharkraeft.dk\/en\/artemisia\/\">Artemisia, Sweet wormwood<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-ea16782edbe729036a867b715831b311\"><a href=\"https:\/\/jegharkraeft.dk\/en\/ashwargandha\/\">Ashwargandha<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-0f6f0162d0357f94eb92f43d8c64850c\"><a href=\"https:\/\/jegharkraeft.dk\/en\/astaxanthin\/\">Astaxanthin<\/a><\/li>\n\n\n\n<li class=\"has-custom-int-link-p-sort-1-color has-text-color has-link-color wp-elements-6b7417181e652727789904c2cfa96c89\"><a href=\"https:\/\/jegharkraeft.dk\/en\/astragalus\/\">Astragalus<\/a><\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"776\" height=\"1164\" src=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/04\/Agaricus-blazei-Murill.jpg\" alt=\"Agaricus blazei Murill symboliseret ved gr\u00f8nt pilleglas fra Swanson med p\u00e5skriften Agaricus Blazei Mushroom Extract, \" class=\"wp-image-8216\" style=\"aspect-ratio:3\/2;object-fit:cover;width:550px\" srcset=\"https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/04\/Agaricus-blazei-Murill.jpg 776w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/04\/Agaricus-blazei-Murill-600x900.jpg 600w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/04\/Agaricus-blazei-Murill-200x300.jpg 200w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/04\/Agaricus-blazei-Murill-683x1024.jpg 683w, https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/04\/Agaricus-blazei-Murill-768x1152.jpg 768w\" sizes=\"auto, (max-width: 776px) 100vw, 776px\" \/><\/figure>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull is-style-default has-global-padding is-layout-constrained wp-container-core-group-is-layout-b040ace0 wp-block-group-is-layout-constrained has-background\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--60);padding-right:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--60);padding-left:var(--wp--preset--spacing--20);background-image:url(&apos;https:\/\/jegharkraeft.dk\/wp-content\/uploads\/2025\/04\/Agaricus-blazei-Murill.jpg&apos;);background-position:44% 36%;background-size:cover;\">\n<div class=\"gb-element-906497af\">\n<h1 class=\"wp-block-heading\" id=\"agaricus-blazei-murill\"><span class=\"ez-toc-section\" id=\"Agaricus_blazei_Murill_ABM_medicinal_mushroom_and_cancer\"><\/span>Agaricus blazei Murill (ABM) (medicinal mushroom) and cancer<span class=\"ez-toc-section-end\"><\/span><\/h1>\n\n\n\n<h4 class=\"wp-block-heading\">What is Agaricus blazei Murill (ABM)?<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Agaricus blazei Murill (ABM) is an edible medicinal mushroom with a characteristic almond-like aroma. It originally hails from the Serra do Caf\u00e9 region in Brazil. Locally, it became known as &#8220;Cogumelo do Sol&#8221; (Mushroom of the Sun) or &#8220;Cogumelo de Deus&#8221; (Mushroom of God), reflecting the high regard it held among the local population.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">History<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Traditionally, ABM was used to promote general health and vitality, strengthen the immune system, and prevent various diseases. Its popularity spread internationally in the late 20th century, particularly in Japan, where extensive research began to uncover its potential health benefits. Traditional use, combined with modern scientific interest, has cemented ABM&#8217;s status as a valuable medicinal mushroom.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Mechanisms_of_Action\"><\/span>Mechanisms of Action<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The health-promoting effects of ABM are being intensively studied. Bioactive components such as polysaccharides (including beta-glucans), sterols (ergosterol), triterpenes, and fatty acids are believed to play a central role.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Immunomodulatory Effects<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Beta-glucans in ABM interact with immune cells (macrophages, neutrophils, NK cells) via receptors such as Dectin-1, which activates immunological reactions.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Macrophages:<\/strong> Imagine them as the &#8220;scavenger cells&#8221; of the body. When ABM is present, these scavenger cells become more active. They get better at &#8220;eating&#8221; and clearing out things that shouldn&#8217;t be there, such as harmful particles. At the same time, they begin sending important &#8220;messages&#8221; (cytokines are such messages) around the body that help manage the immune system, fight inflammation, and influence how cells grow and develop.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>NK cells:<\/strong> You can think of these as the body&#8217;s &#8220;killer cells&#8221; against diseased cells, including those infected with viruses or that have become cancer cells. When ABM activates them, they become even better at finding and destroying these diseased cells. They also begin producing more of the &#8220;messages&#8221; (IFN-$\\gamma$ is one of them) that help other parts of the immune system do their job.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Neutrophils improve their ability to migrate to sites of infection and fight microorganisms.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ABM also affects the maturation of dendritic cells, which are important for adaptive immune responses, potentially leading to a more effective immune response against cancer cells.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Anti-angiogenic Effects<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">ABM&#8217;s bioactive components can inhibit angiogenesis (the formation of new blood vessels), which is necessary for the growth and spread of cancer tumors. They are believed to reduce the production of VEGF, a protein that stimulates blood vessel growth, thereby potentially limiting the blood supply to tumors.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Antiproliferative and Cytotoxic Effects<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">In vitro studies show that ABM extracts can inhibit growth and kill cancer cells by inducing apoptosis, disrupting the cell cycle, and inhibiting growth signaling pathways. Polysaccharides and sterols in ABM are being investigated for their contributions to these effects. Further in vivo research is required to confirm clinical relevance.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Anti-inflammatory Effects<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">ABM extracts can reduce inflammation by modulating the production of pro-inflammatory cytokines. Beta-glucans and polysaccharides are believed to influence signaling pathways involved in inflammation, potentially creating a less favorable environment for cancer cell growth.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Potential_as_Supplementary_Treatment_for_Cancer\"><\/span>Potential as Supplementary Treatment for Cancer<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">ABM has potential as a supplement to cancer treatment and may potentially improve outcomes and quality of life, but should not replace established treatment.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Immune Support<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">ABM&#8217;s immunomodulatory properties can help maintain or restore immune function, which is often weakened by chemotherapy and radiation therapy, thereby potentially improving tolerance to treatment and helping to fight infections.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Synergy with Conventional Treatment<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Research suggests that ABM extracts <em>in vitro<\/em> and <em>in vivo<\/em> can increase cancer cells&#8217; sensitivity to chemotherapy and radiation, possibly by affecting signaling pathways in the cancer cells. For example, ABM can enhance cisplatin&#8217;s inhibitory effect on cancer cell growth.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Inhibition of Metastasis<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">ABM&#8217;s anti-angiogenic and immunomodulatory properties can potentially inhibit metastasis by limiting blood vessel growth to tumors and strengthening the immune system&#8217;s ability to destroy circulating cancer cells.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Benefits_of_Agaricus_blazei_Murill\"><\/span>Benefits of Agaricus blazei Murill<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">ABM can offer several benefits as a supplement to cancer treatment.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Holistic Support for the Body<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">ABM contains vitamins, minerals, and amino acids that can support bodily functions, energy levels, and the nervous system under the stress of cancer treatment.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Natural Origin and Good Tolerance<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">ABM is a natural mushroom that is generally well-tolerated in recommended doses and may be attractive to those seeking complementary treatment forms.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Broad-Spectrum Effect on the Immune System<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">ABM can balance and optimize immune function, potentially leading to more effective combat against cancer cells and better management of infections.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Potential for Long-Term Use<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">ABM has potential for long-term use as a supportive treatment, which can be important for patients requiring prolonged immune support. Always consult a practitioner regarding duration.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Contribution to Mental and Emotional Well-being<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Improved quality of life and fewer side effects can indirectly improve mental and emotional well-being by increasing energy and mood.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Disadvantages and Limitations<\/h4>\n\n\n\n<h4 class=\"wp-block-heading\">Product Quality<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">The quality of ABM products varies depending on growth, harvesting, and processing, which can affect efficacy. Choose products from reliable manufacturers with quality control.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Interactions with Medication<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">ABM can interact with blood-thinning medication (e.g., warfarin) and potentially affect the metabolism of certain drugs via liver enzymes. Always inform your practitioner about ABM use.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Gastrointestinal Issues<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Some may experience mild issues such as bloating, nausea, or diarrhea, especially at higher doses. Start low and increase the dose gradually.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Lack of Large Research Trials<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Many clinical studies are small with methodological limitations. Larger, well-designed studies are needed to confirm benefits and establish optimal doses. Much knowledge comes from <em>in vitro<\/em> and <em>in vivo<\/em> studies.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Clinical Studies<\/h4>\n\n\n\n<h4 class=\"wp-block-heading\">Studies on Immunological Response<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Some studies show that ABM can stimulate immune cells such as NK cells and macrophages as well as increase cytokine production in cancer patients. One study showed improvement in patients with myelodysplastic syndrome.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Studies on Specific Cancer Types<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Studies have investigated ABM in prostate cancer (stabilizing effect on PSA) and liver cancer (improved liver function and possible prolonged survival in combination with standard treatment).<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Safety<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">ABM is generally safe in recommended doses, with mild, transient gastrointestinal side effects in some individuals.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Autoimmune Diseases<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Caution is advised for autoimmune diseases due to potential immune stimulation. Consult a practitioner.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Bleeding Disorders and Surgery<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Exercise caution with bleeding disorders or before surgery due to potential interaction with blood-thinning medication. Stop use a few weeks before surgery.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Pregnancy and Breastfeeding<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Avoid use during pregnancy and breastfeeding unless recommended by a practitioner due to limited information on safety.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Liver Impact<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Rare cases of liver impact have been reported. Be aware of symptoms and seek medical attention if problems arise. Product quality may play a role.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Dispensing and Application<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">ABM is available as capsules, powder, liquid extracts, and dried mushrooms. Dosage varies; follow product recommendations and consult a practitioner for individual advice. Start low to assess tolerance.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Conclusion<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Agaricus blazei Murill is a medicinal mushroom with significant potential as a supplementary treatment for cancer. Its primary mechanisms of action involve immunomodulation, potential anti-angiogenic, antiproliferative, and anti-inflammatory effects. Clinical studies have shown that ABM can contribute to improving quality of life, reducing certain side effects of conventional treatment, and potentially strengthening the immune response in cancer patients. While results are promising, more extensive research is needed to confirm these effects and establish optimal application protocols.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Overview_of_medicinal_mushrooms_and_cannabis\"><\/span>Overview of medicinal mushrooms and cannabis<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">This overview compares the efficacy and safety of the most commonly used medicinal mushrooms. Cannabis is also included in the overview. This is despite cannabis being biologically a plant and not a mushroom. However, it is often used in the same context when natural symptom relief is desired for cancer patients.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Worth knowing:<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Choice of mushroom:<\/strong> If the goal is to get safely through chemo with the fewest side effects, Turkey Tail is most often the first choice, as it has the fewest contraindications.<\/li>\n\n\n\n<li><strong>Neuropathy:<\/strong> If chemo causes numbness in fingers or nerve damage, Lion&#8217;s Mane is the only mushroom with specific documentation for being able to help with nerve regeneration.<\/li>\n\n\n\n<li><strong>Stop before surgery:<\/strong> A good rule of thumb is to stop all mushrooms, especially Reishi, Chaga, and Cordyceps, as well as fish oil, two weeks before scheduled surgeries due to the risk of bleeding.<\/li>\n<\/ul>\n\n\n<h2 id=\"tablepress-88-name\" class=\"tablepress-table-name tablepress-table-name-id-88\"><span class=\"ez-toc-section\" id=\"Medicinal_mushroom_and_Cannabis\"><\/span>Medicinal mushroom and Cannabis<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n<table id=\"tablepress-88\" class=\"tablepress tablepress-id-88\" aria-labelledby=\"tablepress-88-name\">\n<thead>\n<tr class=\"row-1\">\n\t<th class=\"column-1\">Name<\/th><th class=\"column-2\">Primary Effect<\/th><th class=\"column-3\">Use in Cancer<\/th><th class=\"column-4\">Name<\/th><th class=\"column-5\">Important Caution<\/th>\n<\/tr>\n<\/thead>\n<tbody class=\"row-striping row-hover\">\n<tr class=\"row-2\">\n\t<td class=\"column-1\">Agaricus blazei<\/td><td class=\"column-2\">Very powerful immune activation. High content of Beta-1,3\/1,6-glucans.<\/td><td class=\"column-3\">Aggressive support. Used to significantly boost NK-cell activity.<\/td><td class=\"column-4\">Agaricus blazei<\/td><td class=\"column-5\">May affect liver enzymes. Should be used with caution in liver disease or heavy liver-taxing chemo.<\/td>\n<\/tr>\n<tr class=\"row-3\">\n\t<td class=\"column-1\">Cannabis: CBD<\/td><td class=\"column-2\">Anxiolytic and muscle relaxant. Anti-inflammatory.<\/td><td class=\"column-3\">Quality of life. Relieves restlessness, anxiety, muscle tension, and sleep problems without a high.<\/td><td class=\"column-4\">Cannabis: CBD<\/td><td class=\"column-5\">Interaction with medication. Can inhibit the liver&#8217;s breakdown of chemotherapy (CYP450).<\/td>\n<\/tr>\n<tr class=\"row-4\">\n\t<td class=\"column-1\">Cannabigerol (CBG)<\/td><td class=\"column-2\">Neuroprotective and appetite stimulant. Blocks TRPM8 channels (growth signals) in cells.<\/td><td class=\"column-3\">Antitumour support. Targeted use for growth in colon and brain, and against loss of weight and muscle mass.<\/td><td class=\"column-4\">Cannabigerol (CBG)<\/td><td class=\"column-5\">Interaction with liver enzymes (CYP450). May affect the concentration of blood thinners and certain types of epilepsy medication.<\/td>\n<\/tr>\n<tr class=\"row-5\">\n\t<td class=\"column-1\">Cannabis: THC<\/td><td class=\"column-2\">Antiemetic and appetite stimulant. Psychoactive (euphoric).<\/td><td class=\"column-3\">Acute relief. Against severe nausea, vomiting, and weight loss.<\/td><td class=\"column-4\">Cannabis: THC<\/td><td class=\"column-5\">Driving ban. Psychoactive side effects. Sedative effect.<\/td>\n<\/tr>\n<tr class=\"row-6\">\n\t<td class=\"column-1\">Chaga<\/td><td class=\"column-2\">Powerful antioxidant (SOD). Contains Betulin and Betulinic acid. Protects against oxidative stress.<\/td><td class=\"column-3\">Restorative. Used for general strengthening of the body under pressure.<\/td><td class=\"column-4\">Chaga<\/td><td class=\"column-5\">High oxalate content (risk of kidney stones). Blood-thinning. Interacts with insulin (lowers blood sugar).<\/td>\n<\/tr>\n<tr class=\"row-7\">\n\t<td class=\"column-1\">Cordyceps<\/td><td class=\"column-2\">Energizing. Increases oxygen uptake (ATP) and kidney function.<\/td><td class=\"column-3\">Lung function. Counteracts shortness of breath and cancer-related fatigue.<\/td><td class=\"column-4\">Cordyceps<\/td><td class=\"column-5\">May over-activate the immune system in autoimmune diseases. Blood-thinning.<\/td>\n<\/tr>\n<tr class=\"row-8\">\n\t<td class=\"column-1\">Lion&#8217;s Mane<\/td><td class=\"column-2\">Nerve regenerating. Stimulates growth of nerve cells (NGF).<\/td><td class=\"column-3\">Neuropathy. Counteracts sensory disturbances in fingers\/feet and memory difficulties (chemo brain).<\/td><td class=\"column-4\">Lion&#8217;s Mane<\/td><td class=\"column-5\">May lower blood sugar. Mild blood-thinning effect.<\/td>\n<\/tr>\n<tr class=\"row-9\">\n\t<td class=\"column-1\">Maitake<\/td><td class=\"column-2\">Immune-activating (D-fraction). Strong stimulation of macrophages.<\/td><td class=\"column-3\">Immune boost. Often used to activate the body&#8217;s own defense against cancer cells.<\/td><td class=\"column-4\">Maitake<\/td><td class=\"column-5\">May lower blood sugar. Can enhance the effect of blood-thinning medication.<\/td>\n<\/tr>\n<tr class=\"row-10\">\n\t<td class=\"column-1\">Pau D\u2019Arco<\/td><td class=\"column-2\">Potent antifungal and anti-inflammatory. Contains Lapachol.<\/td><td class=\"column-3\">Micro-environment. Used to purify the blood and combat fungal infections (Candida), which are often seen with a weakened immune system.<\/td><td class=\"column-4\">Pau D\u2019Arco<\/td><td class=\"column-5\">Blood-thinning. Must not be combined with blood-thinning medication or used prior to surgical procedures.<\/td>\n<\/tr>\n<tr class=\"row-11\">\n\t<td class=\"column-1\">Pao Pereira<\/td><td class=\"column-2\">Inhibits replication of abnormal cells. Penetrates the blood-brain barrier.<\/td><td class=\"column-3\">Targeted cell division. Often used for prostate cancer and cancers of the central nervous system (brain).<\/td><td class=\"column-4\">Pao Pereira<\/td><td class=\"column-5\">Generally well-tolerated, but should be taken under guidance to ensure correct dosage relative to conventional treatment.<\/td>\n<\/tr>\n<tr class=\"row-12\">\n\t<td class=\"column-1\">Poria cocos<\/td><td class=\"column-2\">Diuretic and calming. Supports spleen and kidney function. Contains Pachyman.<\/td><td class=\"column-3\">Fluid retention. Helps against edema and mucus. Calms restlessness and racing thoughts.<\/td><td class=\"column-4\">Poria cocos<\/td><td class=\"column-5\">Acts as a diuretic. Be mindful of electrolyte balance if taking other diuretic medication.<\/td>\n<\/tr>\n<tr class=\"row-13\">\n\t<td class=\"column-1\">Reishi<\/td><td class=\"column-2\">Calming and immune-strengthening. Acts as an adaptogen (stress-reducing) and sleep-promoting.<\/td><td class=\"column-3\">Sleep and stress. Good for finding peace in the body and supporting the immune system between treatments.<\/td><td class=\"column-4\">Reishi<\/td><td class=\"column-5\">Blood-thinning. Must not be used with low platelets or before surgery.<\/td>\n<\/tr>\n<tr class=\"row-14\">\n\t<td class=\"column-1\">Shiitake<\/td><td class=\"column-2\">Immune-stimulating. Source of Lentinan and AHCC.<\/td><td class=\"column-3\">Standard support. Lentinan is used medically to prolong survival in certain types of cancer.<\/td><td class=\"column-4\">Shiitake<\/td><td class=\"column-5\">May in rare cases cause skin rash (Shiitake dermatitis). Contains purines (caution in gout).<\/td>\n<\/tr>\n<tr class=\"row-15\">\n\t<td class=\"column-1\">Turkey Tail<\/td><td class=\"column-2\">Immune-modulating. Supports the immune system (NK cells) without overstimulating. Contains PSK.<\/td><td class=\"column-3\">Chemo support. Often used alongside chemo to counteract immune suppression.<\/td><td class=\"column-4\">Turkey Tail<\/td><td class=\"column-5\">Generally considered safe. Few known interactions (approved drug in Japan as PSK).<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<!-- #tablepress-88 from cache -->\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Back to <a href=\"https:\/\/jegharkraeft.dk\/en\/supplements-alphabetically\/\"><strong>Dietary Supplements<\/strong><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">See also <a href=\"https:\/\/jegharkraeft.dk\/en\/minimer-kemo\/#10nerveproblemer\"><strong>Minimize Side Effects &#8211; Chemo, Nerve Problems<\/strong><\/a><\/p>\n\n\n\n<p class=\"has-custom-menu-links-color has-text-color has-link-color wp-elements-9190cfe395c28e4d2ec89873338ddaa5 wp-block-paragraph\"><a href=\"#menu\">(to menu)<\/a><a href=\"https:\/\/jegharkraeft.dk\/en\/supplements-alphabetically\/\"><\/a><\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Links<\/strong><\/h4>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-69aeaf27a116c01684abc72ed3db8b58 wp-block-paragraph\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2667142521000312\" target=\"_blank\" rel=\"noopener\"><em>Agaricus blazei<\/em>&nbsp;Murrill mushroom: A review on the prevention and treatment of cancer <\/a>(Science Direct)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-5e5909efa863e9dac85b0a29de818ddb wp-block-paragraph\"><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3168293\/\" target=\"_blank\" rel=\"noopener\">The Mushroom&nbsp;<em>Agaricus blazei<\/em>&nbsp;Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1\/Th2 Imbalance and Inflammation<\/a> (NIH)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-fb4caf228bd63333d7aa6bf27c55d19f wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39950425\/\" target=\"_blank\" rel=\"noopener\">The Age-Dependent Anticancer Efficacy of Agaricus blazei Murill Polysaccharide in Colon Cancer<\/a> (PubMed)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-5d05327a2d5f21a67d5e2e3f870604a8 wp-block-paragraph\"><a href=\"https:\/\/www.mskcc.org\/cancer-care\/integrative-medicine\/herbs\/agaricus\" target=\"_blank\" rel=\"noopener\">Agaricus<\/a> (Memorial Sloan Kettering Cancer Center)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-ed92c3d3c05596a51e43f63e29386e5e wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39471924\/\" target=\"_blank\" rel=\"noopener\">Preventive intervention with Agaricus blazei murill polysaccharide exerts anti-tumor immune effect on intraperitoneal metastasis colorectal cancer<\/a> (PubMed)<\/p>\n\n\n\n<p class=\"has-custom-sort-tekst-color has-text-color has-link-color wp-elements-986c17ea61e0bf6092a3b3b03f87d832 wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38097495\/\" target=\"_blank\" rel=\"noopener\">Agaricus blazei Murill extract FA-2-b-\u03b2 inhibits gastric cancer cell proliferation through the mechanisms of cell-cycle blocking and apoptosis by the mitochondrial pathway<\/a> (PubMed)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Page created: <\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">April, 18.25<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-custom-menu-links-color\">\u2764<\/mark><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em><strong>What you read on Jeg har Kr\u00e6fter is not a recommendation. Seek competent guidance.<\/strong><\/em><\/p>\n<\/div>\n<\/div>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Indhold<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/jegharkraeft.dk\/en\/agaricus-blazei-murill\/#Dietary_Supplements_Grouped_by_Effect\" >Dietary Supplements Grouped by Effect<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/jegharkraeft.dk\/en\/agaricus-blazei-murill\/#Dietary_Supplements_Alphabetical\" >Dietary Supplements Alphabetical<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/jegharkraeft.dk\/en\/agaricus-blazei-murill\/#Agaricus_blazei_Murill_ABM_medicinal_mushroom_and_cancer\" >Agaricus blazei Murill (ABM) (medicinal mushroom) and cancer<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/jegharkraeft.dk\/en\/agaricus-blazei-murill\/#Mechanisms_of_Action\" >Mechanisms of Action<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/jegharkraeft.dk\/en\/agaricus-blazei-murill\/#Potential_as_Supplementary_Treatment_for_Cancer\" >Potential as Supplementary Treatment for Cancer<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/jegharkraeft.dk\/en\/agaricus-blazei-murill\/#Benefits_of_Agaricus_blazei_Murill\" >Benefits of Agaricus blazei Murill<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/jegharkraeft.dk\/en\/agaricus-blazei-murill\/#Overview_of_medicinal_mushrooms_and_cannabis\" >Overview of medicinal mushrooms and cannabis<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/jegharkraeft.dk\/en\/agaricus-blazei-murill\/#Medicinal_mushroom_and_Cannabis\" >Medicinal mushroom and Cannabis<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Dietary Supplements Grouped by Effect Dietary Supplements Alphabetical A,. B,. C,. D,. E+F,. G,. H,. I+J+K,. L,. M,. N,. O,. P,. Q,. R,. S,. T,. U+V+Z Agaricus blazei Murill (ABM) (medicinal mushroom) and cancer What is Agaricus blazei Murill (ABM)? Agaricus blazei Murill (ABM) is an edible medicinal mushroom with a characteristic almond-like aroma. It [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":31293,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[374,375,389],"tags":[],"class_list":["post-31294","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-treatments","category-alternative-treatments","category-supplements"],"modified_by":"Hanne Kj\u00e6r Uhlig","wpml_current_locale":"en_US","wpml_translations":[],"_links":{"self":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts\/31294","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/comments?post=31294"}],"version-history":[{"count":4,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts\/31294\/revisions"}],"predecessor-version":[{"id":35276,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/posts\/31294\/revisions\/35276"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/media\/31293"}],"wp:attachment":[{"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/media?parent=31294"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/categories?post=31294"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jegharkraeft.dk\/en\/wp-json\/wp\/v2\/tags?post=31294"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}